(a) Interpretation: The concentrations of the hormones, yielding 50% of maximal binding is to be determined. Concept introduction: The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

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Answer 1

Question

Chapter 14, Problem 21P

Interpretation Introduction

(a)

Interpretation:

The concentrations of the hormones, yielding 50% of maximal binding is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(b)

Interpretation:

Hormone that shows the highest affinity for receptor is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(c)

Interpretation:

Relation between the binding affinity of the hormone-receptor complex and the ability of the hormone to enhance adenylate cyclase activity should be determined.

The mechanism of action of hormone-receptor complex is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(d)

Interpretation:

Experiments should be determined to check whether a G_as protein is a component of signal-transduction pathways.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

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Answer 2

Question

Chapter 14, Problem 21P

Interpretation Introduction

(a)

Interpretation:

The concentrations of the hormones, yielding 50% of maximal binding is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(b)

Interpretation:

Hormone that shows the highest affinity for receptor is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(c)

Interpretation:

Relation between the binding affinity of the hormone-receptor complex and the ability of the hormone to enhance adenylate cyclase activity should be determined.

The mechanism of action of hormone-receptor complex is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(d)

Interpretation:

Experiments should be determined to check whether a G_as protein is a component of signal-transduction pathways.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

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Answer 3

Question

Chapter 14, Problem 21P

Interpretation Introduction

(a)

Interpretation:

The concentrations of the hormones, yielding 50% of maximal binding is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(b)

Interpretation:

Hormone that shows the highest affinity for receptor is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(c)

Interpretation:

Relation between the binding affinity of the hormone-receptor complex and the ability of the hormone to enhance adenylate cyclase activity should be determined.

The mechanism of action of hormone-receptor complex is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(d)

Interpretation:

Experiments should be determined to check whether a G_as protein is a component of signal-transduction pathways.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

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Answer 4

Question

Chapter 14, Problem 21P

Interpretation Introduction

(a)

Interpretation:

The concentrations of the hormones, yielding 50% of maximal binding is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(b)

Interpretation:

Hormone that shows the highest affinity for receptor is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(c)

Interpretation:

Relation between the binding affinity of the hormone-receptor complex and the ability of the hormone to enhance adenylate cyclase activity should be determined.

The mechanism of action of hormone-receptor complex is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(d)

Interpretation:

Experiments should be determined to check whether a G_as protein is a component of signal-transduction pathways.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

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Answer 5

Chapter 14, Problem 21P

Interpretation Introduction

(a)

Interpretation:

The concentrations of the hormones, yielding 50% of maximal binding is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(b)

Interpretation:

Hormone that shows the highest affinity for receptor is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(c)

Interpretation:

Relation between the binding affinity of the hormone-receptor complex and the ability of the hormone to enhance adenylate cyclase activity should be determined.

The mechanism of action of hormone-receptor complex is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Interpretation Introduction

(d)

Interpretation:

Experiments should be determined to check whether a G_as protein is a component of signal-transduction pathways.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Answer 6

Chapter 14, Problem 21P

Interpretation Introduction

(a)

Interpretation:

The concentrations of the hormones, yielding 50% of maximal binding is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Answer 7

Chapter 14, Problem 21P

Interpretation Introduction

(a)

Interpretation:

The concentrations of the hormones, yielding 50% of maximal binding is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Answer 8

Interpretation Introduction

(b)

Interpretation:

Hormone that shows the highest affinity for receptor is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Answer 9

Interpretation Introduction

(b)

Interpretation:

Hormone that shows the highest affinity for receptor is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Answer 10

Interpretation Introduction

(c)

Interpretation:

Relation between the binding affinity of the hormone-receptor complex and the ability of the hormone to enhance adenylate cyclase activity should be determined.

The mechanism of action of hormone-receptor complex is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Answer 11

Interpretation Introduction

(c)

Interpretation:

Relation between the binding affinity of the hormone-receptor complex and the ability of the hormone to enhance adenylate cyclase activity should be determined.

The mechanism of action of hormone-receptor complex is to be determined.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Answer 12

Interpretation Introduction

(d)

Interpretation:

Experiments should be determined to check whether a G_as protein is a component of signal-transduction pathways.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Answer 13

Interpretation Introduction

(d)

Interpretation:

Experiments should be determined to check whether a G_as protein is a component of signal-transduction pathways.

Concept introduction:

The first step of hormone’s signaling pathway is binding to a receptor present inside the cell or on the surface of the cell. Stability of the hormone-receptor complex is reflected by the affinity. Higher the affinity, stronger is the relation between the hormone and receptor.

Answer 14

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Answer 15

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Answer 16

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Answer 17

Ch. 14 - Prob. 1P Ch. 14 - Prob. 2P Ch. 14 - Prob. 3P Ch. 14 - Prob. 4P Ch. 14 - Prob. 5P Ch. 14 - Prob. 6P Ch. 14 - Prob. 7P Ch. 14 - Prob. 8P Ch. 14 - Prob. 9P Ch. 14 - Prob. 10P

Solution Summary: The author explains that the concentrations of the hormones yielding 50% of maximal binding are to be determined.

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Chapter 14 Solutions