Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 14, Problem 20P
Interpretation Introduction
Interpretation:
A potential drawback of drugs that are ATP-competitive inhibitor should be determined.
Concept introduction:
A competitive inhibitor resembles the substrate that binds at the active site of the enzyme. Competitive inhibitors are mainly used in making drugs. For instance, during chemotherapy, a drug, named methotrexate is used which acts as a competitive inhibitor. Moreover, if the concentration of the substrate is increased, then the effect of a competitive inhibitor can be reduced.
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