Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 14, Problem 17P
Interpretation Introduction
Interpretation:
Mechanism for NGF signaling pathways and the secondary messenger produced during this should be determined.
Concept introduction:
Nerve growth factor is a neuropeptide that is responsible for the growth, proliferation, maintenance, and survival of the certain target neurons. NGF binds to two kinds of receptors, tropomyosin receptor kinase A, and low-affinity NGF receptor. The mutation in any of these receptors can lead to neurodegenerative disorders.
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