
Concept explainers
In eukaryotic cells, transcription cannot begin until
- A. the two DNA strands have completely separated and exposed the promoter.
- B. several transcription factors have bound to the promoter.
- C. the 5’ caps are removed from the mRNA.
- D. the DNA introns are removed from the template.

Introduction:
DNA (deoxyribonucleic acid) consists of genetic instructions that are necessary for the development and functioning of living cells and it can be transmitted from parents to offspring. Transcription is the process that involves the synthesis of RNA (ribonucleic acid) from DNA.
Answer to Problem 1TYU
Correct answer:
In eukaryotic cells, transcription cannot begin until several transcription factors have bound to the promoter. Therefore, option (B) is correct.
Explanation of Solution
Reason for the correct statement:
There are certain differences between prokaryotic transcription and eukaryotic transcription. In the case of prokaryotic transcription, the transcription can begin without the involvement of transcriptional factors. However, in eukaryotic transcription, the transcription is initiated only when several transcription factors bind to it. These transcription factors get dissociated once the transcription is initiated.
Option (B) is given as “several transcription factors have bound to the promoter”.
“The transcription cannot begin until transcription factors have bound to the promoter in eukaryotic cells” is the right answer.
Hence, option (B) is correct.
Reasons for the incorrect statements:
Option (A) is given as “the two DNA strands have completely separated and exposed the promoter”.
In transcription, the double-stranded DNA will separate only after the binding of RNA polymerase to the promoter region. RNA polymerase will attach to DNA only in the presence of transcriptional factors. Therefore, option (A) is the wrong answer.
Option (C) is given as “the 5' caps are removed from the
The
Option (D) is given as “the DNA introns are removed from the template”.
The introns are the non-coding nucleotide sequences, which are spliced before the formation of the final product of mRNA. The transcription process does not require the removal of introns from the template for the initiation of the process. Therefore, option (D) is the wrong answer.
Hence, options (A), (C), and (D) are incorrect.
Transcription cannot begin until the transcription factors have bound to the promoter in the eukaryotic cells.
Want to see more full solutions like this?
Chapter 14 Solutions
Campbell Biology in Focus (2nd Edition)
Additional Science Textbook Solutions
SEELEY'S ANATOMY+PHYSIOLOGY
Genetics: From Genes to Genomes
Chemistry: An Introduction to General, Organic, and Biological Chemistry (13th Edition)
Campbell Essential Biology (7th Edition)
- What is this?arrow_forwardMolecular Biology A-C components of the question are corresponding to attached image labeled 1. D component of the question is corresponding to attached image labeled 2. For a eukaryotic mRNA, the sequences is as follows where AUGrepresents the start codon, the yellow is the Kozak sequence and (XXX) just represents any codonfor an amino acid (no stop codons here). G-cap and polyA tail are not shown A. How long is the peptide produced?B. What is the function (a sentence) of the UAA highlighted in blue?C. If the sequence highlighted in blue were changed from UAA to UAG, how would that affecttranslation? D. (1) The sequence highlighted in yellow above is moved to a new position indicated below. Howwould that affect translation? (2) How long would be the protein produced from this new mRNA? Thank youarrow_forwardMolecular Biology Question Explain why the cell doesn’t need 61 tRNAs (one for each codon). Please help. Thank youarrow_forward
- Molecular Biology You discover a disease causing mutation (indicated by the arrow) that alters splicing of its mRNA. This mutation (a base substitution in the splicing sequence) eliminates a 3’ splice site resulting in the inclusion of the second intron (I2) in the final mRNA. We are going to pretend that this intron is short having only 15 nucleotides (most introns are much longer so this is just to make things simple) with the following sequence shown below in bold. The ( ) indicate the reading frames in the exons; the included intron 2 sequences are in bold. A. Would you expected this change to be harmful? ExplainB. If you were to do gene therapy to fix this problem, briefly explain what type of gene therapy youwould use to correct this. Please help. Thank youarrow_forwardMolecular Biology Question Please help. Thank you Explain what is meant by the term “defective virus.” Explain how a defective virus is able to replicate.arrow_forwardMolecular Biology Explain why changing the codon GGG to GGA should not be harmful. Please help . Thank youarrow_forward
- Stage Percent Time in Hours Interphase .60 14.4 Prophase .20 4.8 Metaphase .10 2.4 Anaphase .06 1.44 Telophase .03 .72 Cytukinesis .01 .24 Can you summarize the results in the chart and explain which phases are faster and why the slower ones are slow?arrow_forwardCan you circle a cell in the different stages of mitosis? 1.prophase 2.metaphase 3.anaphase 4.telophase 5.cytokinesisarrow_forwardWhich microbe does not live part of its lifecycle outside humans? A. Toxoplasma gondii B. Cytomegalovirus C. Francisella tularensis D. Plasmodium falciparum explain your answer thoroughly.arrow_forward
- Select all of the following that the ablation (knockout) or ectopoic expression (gain of function) of Hox can contribute to. Another set of wings in the fruit fly, duplication of fingernails, ectopic ears in mice, excess feathers in duck/quail chimeras, and homeosis of segment 2 to jaw in Hox2a mutantsarrow_forwardSelect all of the following that changes in the MC1R gene can lead to: Changes in spots/stripes in lizards, changes in coat coloration in mice, ectopic ear formation in Siberian hamsters, and red hair in humansarrow_forwardPleiotropic genes are genes that (blank) Cause a swapping of organs/structures, are the result of duplicated sets of chromosomes, never produce protein products, and have more than one purpose/functionarrow_forward
- Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax CollegeBiology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningComprehensive Medical Assisting: Administrative a...NursingISBN:9781305964792Author:Wilburta Q. Lindh, Carol D. Tamparo, Barbara M. Dahl, Julie Morris, Cindy CorreaPublisher:Cengage LearningHuman Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning





