EBK MICROBIOLOGY:W/DISEASES BY BODY...-
EBK MICROBIOLOGY:W/DISEASES BY BODY...-
5th Edition
ISBN: 9780134608242
Author: BAUMAN
Publisher: PEARSON
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Chapter 13, Problem 12CT
Summary Introduction

To answer:

Absence of viral envelope and its effect on the virulence of the virus.

Introduction:

The viruses are obligate organisms that show signs of life only inside a host. Outside the host, they either die or do not show any sign of life. They invade the host cell to carry out their function like replication. A particular virus infects a particular host cell. The invaded host cell acts as machinery for the viruses. Depending upon the state of the virus, they can carry out either lytic cycle or lysogenic cycle.

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In electron micrographs of HSV infection, it can be seen that the intact virus initially reacts with cell-surface proteoglycans, then with specific receptors. This is later followed by viral capsids docking with nuclear pores. Afterward, the capsids go from being full to being "empty." Which of the following statements best fits these observations? The viral envelope is not required for infectivity, since the envelope does not enter the nucleus. The viral envelope mediates entry into the cell, the capsid mediates entry into the nuclear membrane, and the genome is all that enters the nucleus. Only the genetic material of the virus is involved in the cell's infectivity, and is injected into the host cell like the genome of a phage. Viral capsids are needed for the cell to become infected; since the full capsids enter the nucleus.
Which of the following statements is TRUE concerning viral envelopes? Only viruses with envelopes have their contents enclosed by a layer containing lipids Only viruses without envelopes interact with receptor proteins on the surface of the host cell. Only viruses without envelopes can release their genetic material into the cytoplasm of the host. Only viruses with envelopes package their genetic material by engulfing it.
Rhinovirus, the most common cause of colds, do not have a lipid envelope. Compared to enveloped viruses these and other nonenveloped viruses tend to remain infectious outside the body longer, are more likely to be spread by contact with surfaces, and are likely to be rendered harmless by exposure to hand sanitizer or hand washing. Explain how the lack of an envelope could contribute to these characteristics.
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