Concept explainers
To explain:
The chance of having a hemophilic son from a hemophilic father and a carrier mother.
Introduction:
Genetic disorders result from inheritance of traits which are either dominant or recessive. Traits that are controlled by genes located on sex chromosomes; X chromosomes in particular are called sex- linked traits or X- linked traits.Hemophilia is a sex- linked recessive disorder caused by a lack of blood clotting agent called factor VIII.

Answer to Problem 11STP
When a mother is a carrier of the gene, and father suffers from hemophilia;
There is 50% chance that son will also carry the gene and express it.
Explanation of Solution
Traits that are controlled by genes located on sex chromosomes; X chromosomes in particular are called sex- linked traits or X- linked traits. Since males have only X chromosome, they are affected by recessive X- linked traits more often than females. Females usually do not express the recessive trait as other X chromosome will mask the effect of the recessive trait.
According to the given information, father is hemophilic but mother is a carrier of the trait. The genotypes of the offspring can be checked with the help of a Punnett square.
Let XH= Normal
Xh= hemophilia
Y= Y chromosome
The mother is a carrier of thedisease so she has the recessive allele for hemophilia on one of her X chromosomes. The father is hemophilic so he has the recessive allele on the X chromosome.
Xh | Y | |
XH | XHXh | XHY |
Xh | XhXh | XhY |
Out of the two sons, only one son will have hemophilia as he receives the recessive allele from his mother. So there is 50% chance of a boy to have hemophilia.
Chapter 13 Solutions
EP BIOLOGY 2012-STUDENTWORKS ONLINE
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