Microbiology: A Systems Approach
4th Edition
ISBN: 9780073402437
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 12.2, Problem 5AYP
Summary Introduction
To explain:
The concept of selective toxicity.
Concept introduction:
Antimicrobial agents are commonly used to treat microbial infections. Antimicrobial agents differ in their mode of action, including, inhibition of cell wall, inhibition of protein and
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 12 Solutions
Microbiology: A Systems Approach
Ch. 12.1 - State the main goal of antimicrobial treatment.Ch. 12.1 - Identify sources of the most commonly used...Ch. 12.1 - Summarize two methods for testing antimicrobial...Ch. 12.1 - Prob. 4AYPCh. 12.2 - Prob. 5AYPCh. 12.2 - Describe the five major targets of antimicrobial...Ch. 12.2 - Identify which categories of drugs are most...Ch. 12.3 - Prob. 2CFCh. 12.3 - Prob. 8AYPCh. 12.3 - Trace the development of penicillin...
Ch. 12.3 - Prob. 10AYPCh. 12.3 - Prob. 11AYPCh. 12.3 - Prob. 12AYPCh. 12.3 - Prob. 13AYPCh. 12.3 - Identify the cellular target of quinolones, and...Ch. 12.3 - Prob. 15AYPCh. 12.3 - Prob. 16AYPCh. 12.3 - Prob. 17AYPCh. 12.3 - Prob. 18AYPCh. 12.3 - Describe two major modes of action of antiviral...Ch. 12.4 - Prob. 20AYPCh. 12.4 - Prob. 21AYPCh. 12.4 - Discuss at least three novel antimicrobial...Ch. 12.5 - Distinguish between drug toxicity and allergic...Ch. 12.5 - Prob. 24AYPCh. 12 - Prob. 1CFCh. 12 - Prob. 1MCQCh. 12 - Prob. 2MCQCh. 12 - Prob. 3MCQCh. 12 - Microbial resistance to drugs is acquired through...Ch. 12 - Prob. 5MCQCh. 12 - Prob. 6MCQCh. 12 - Prob. 7MCQCh. 12 - Which of the following modes of action would be...Ch. 12 - Prob. 9MCQCh. 12 - Prob. 10MCQCh. 12 - Prob. 11TFCh. 12 - Prob. 12TFCh. 12 - Biofilms are difficult to treat and do not always...Ch. 12 - Prob. 14TFCh. 12 - Prob. 15TFCh. 12 - Construct a paragraph describing the...Ch. 12 - Prob. 2CTQCh. 12 - Prob. 3CTQCh. 12 - Prob. 4CTQCh. 12 - Prob. 5CTQCh. 12 - Prob. 6CTQCh. 12 - Antibiotic-resistance genes, as well as other...Ch. 12 - Prob. 8CTQCh. 12 - Prob. 9CTQCh. 12 - Prob. 10CTQCh. 12 - Prob. 1CCCh. 12 - Prob. 2CCCh. 12 - Figure 12.5. Where could penicillinase affect each...Ch. 12 - From chapter 6, process figure 6.14a. Describe as...Ch. 12 - Prob. 1CM
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Briefly explain the 6 domain of interprofessional collaboration: Role clarification, Team functioning, Interprofessional communication, Patient/client/family/community-centered care, Interprofessional conflict resolution, Collaborative leadership. Provide a specific negative events that nursing student would observe in a clinical setting for each domain.arrow_forwardwhat is an intermittent water course and what kind of fish habitat it would providearrow_forwardwhy are native freshwater mussels are an important part of great lakes ecosystemarrow_forward
- what morphological features differentiate the lamprey species and other species in the great lakesarrow_forwardThere are a wide range of therapeutic applications available as options for patients. Medical professionals should be aware of these applications so they can make informed recommendations to patients. To gain a better understanding of some therapeutic applications and how they are related to RNA and mRNA, research long non-coding RNA. Respond to the following in a minimum of 175 words: What is lncRNA and what does it do? How does IncRNA differ from mRNA? What are some therapeutic applications associated with lncRNA? Think about possible future uses of this application. What are the advantages and disadvantages of this application and its continued use?arrow_forwardfour fish or mussel species that are native to the great lakesarrow_forward
- There are a wide range of therapeutic applications available as options for patients. Medical professionals should be aware of these applications so they can make informed recommendations to patients. To gain a better understanding of some therapeutic applications and how they are related to RNA and mRNA, research long non-coding RNA. Respond to the following in a minimum of 175 words: What is lncRNA and what does it do? How does IncRNA differ from mRNA? What are some therapeutic applications associated with lncRNA? Think about possible future uses of this application. What are the advantages and disadvantages of this application and its continued use?arrow_forwardfour physial characteristics of a fish or a mussel that would help you identify it to a speciesarrow_forwarddescribe what you would do in this situation, you are working ona. river and it will take 20 minutes by boat to get back to the field truck, you are 1 hour from finishing the field work on the last day of field trip. you hear thunder int he dsitnace, what did you do?arrow_forward
- unu grow because auxin is still produced in the tip to Another of Boysen and Jensen's experiments included the use of mica, explain why one of the shoots was able to show phototropism and the other was not. Mica Wafer Ligh c. They then t but this time permeable n shoot. Why phototropis Light Mica Wafer Coleoptile tips Tips removed: agar Explain why the shoo direction after the ag the cut shoot, even tarrow_forwardDiscussion entries must be at least 250 words to fulfill the assignment requirements. You must complete your entry before you will be able to see the responses of other students. Responses to other students are encouraged but not required. Grading for discussion entries will be based on application of course concepts, proper grammar, and correct punctuation. Read one the attached article and explore the Human Development Index (https://hdr.undp.org/data-center/human-development-index#/indicies/HDI). In your opinion, is the Human Development Index a good measure of the well- being of the people of a nation? Are the items measured in the HDI valid and relevant in the modern global economy? How are they related to the political economy of a nation? The attached articles propose some alternative measures of well-being. In your opinion, are there other measures of well-being that might be better alternatives to the items in the current HDI?arrow_forwardA patient visits her doctor with symptoms typical of a bladder infection. She is immediately prescribed an 800 mgdose of antibiotic (bioavailability = 1/2, t½ = 12 h). The corresponding plasma concentration of drug is found to be 96 micrograms/ml. What is the volume of distribution of this drug? Please round to the nearest liter.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Essentials of Pharmacology for Health ProfessionsNursingISBN:9781305441620Author:WOODROWPublisher:CengageBasic Clinical Lab Competencies for Respiratory C...NursingISBN:9781285244662Author:WhitePublisher:Cengage
Essentials of Pharmacology for Health Professions
Nursing
ISBN:9781305441620
Author:WOODROW
Publisher:Cengage
Basic Clinical Lab Competencies for Respiratory C...
Nursing
ISBN:9781285244662
Author:White
Publisher:Cengage
Drug Abuse, Causes, Signs and Symptoms, Diagnosis and Treatment.; Author: Medical Centric;https://www.youtube.com/watch?v=b6Dte96WdqM;License: Standard youtube license