Microbiology: A Systems Approach
Microbiology: A Systems Approach
4th Edition
ISBN: 9780073402437
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
Question
Book Icon
Chapter 12, Problem 1CF
Summary Introduction

To determine:

The term “New Delhi metallo-beta-lactamase 1 (NDM-1)”.

Concept introduction:

NDM-1 (New Delhi metallo-beta-lactamase 1) is an enzyme encoded by plasmid, which is able to make bacteria resistant to a wide range of β-lactam antibiotics. This is because the enzyme is able to break the beta-lactam ring of many antibiotics.

Expert Solution
Check Mark

Explanation of Solution

NDM -1 is also termed as “Indian superbug”. blaNDM-1 is the gene which codes for beta-lactamase. β-lactamase and this gene were first discovered in people who had travelled to India or South Asia in 2008.

Conclusion

NDM-1 is an enzyme that can resist a wide range of antibiotics.

Summary Introduction

To determine:

How NDM-1 coding gene spread among bacteria.

Concept introduction:

NDM-1 (New Delhi metallo-beta-lactamase 1) is an enzyme encoded by plasmid which is able to make bacteria resistant to a wide range of β-lactam antibiotics. This is because the enzyme is able to break the beta-lactam ring of many antibiotics.

Expert Solution
Check Mark

Explanation of Solution

The beta-lactamase coding gene is easily transfers from bacteria to bacteria through horizontal gene transfer. Horizontal gene transfer is also termed as lateral gene transfer. It is the primary means of spread of antibiotic resistance among bacteria. It is a way through which genetic material is transferred between organisms.

Conclusion

blaNDM-1 gene is transferred to other bacteria through horizontal gene transfer.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!
Students have asked these similar questions
Ch.23 How is Salmonella able to cross from the intestines into the blood? A. it is so small that it can squeeze between intestinal cells B. it secretes a toxin that induces its uptake into intestinal epithelial cells C. it secretes enzymes that create perforations in the intestine D. it can get into the blood only if the bacteria are deposited directly there, that is, through a puncture — Which virus is associated with liver cancer? A. hepatitis A B. hepatitis B C. hepatitis C D. both hepatitis B and C — explain your answer thoroughly
Ch.21 What causes patients infected with the yellow fever virus to turn yellow (jaundice)? A. low blood pressure and anemia B. excess leukocytes C. alteration of skin pigments D. liver damage in final stage of disease — What is the advantage for malarial parasites to grow and replicate in red blood cells? A. able to spread quickly B. able to avoid immune detection C. low oxygen environment for growth D. cooler area of the body for growth — Which microbe does not live part of its lifecycle outside humans? A. Toxoplasma gondii B. Cytomegalovirus C. Francisella tularensis D. Plasmodium falciparum — explain your answer thoroughly
Ch.22 Streptococcus pneumoniae has a capsule to protect it from killing by alveolar macrophages, which kill bacteria by… A. cytokines B. antibodies C. complement D. phagocytosis — What fact about the influenza virus allows the dramatic antigenic shift that generates novel strains? A. very large size B. enveloped C. segmented genome D. over 100 genes — explain your answer thoroughly

Chapter 12 Solutions

Microbiology: A Systems Approach

Knowledge Booster
Background pattern image
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Text book image
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Text book image
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Text book image
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Text book image
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Text book image
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education