Chapter 12, Problem 83P

Summary Introduction

To explain: The reason why individuals with a prosthetic heart valve will still be required to take ASA for rest of the life and the reason why such patient will still require antibiotic coverage before invasive procedures.

Introduction: Rheumatic fever is an acute systemic inflammatory condition that occurs due to complication of group A Streptococcus infection. Acute rheumatic fever occurs when the connective tissues of the body become swollen. Acetylsalicylic acid (aspirin) or ASA is an anti-inflammatory agent that decreases the synthesis of prostaglandin in the swollen region and reduces the inflammatory response