Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Chapter 12, Problem 33CTQ
People with trisomy 21 develop Down’s syndrome. What law of
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Clara has polydactyly, an autosomal dominant that is 80% penetrant. Clara
inherited her polydactyly from her mother, her father had no polydactyly in his
family. She has an extra toe on her left foot. Her husband Ralph has no
polydactyly in his family.
A) What is the chance that Clara will have a child that will inherit polydactyly?
B) What is the chance that the child will express polydactyly.
You can leave these as un-calculated equations.
What is the frequency of sickle cell disease (anemia)?
https://ghr.nlm.nih.gov/condition/sickle-cell-disease#inheritance
https://www.cdc.gov/ncbddd/sicklecell/traits.html
What is heterozygote advantage. How does this phenomenon explain the preponderance of disorders such as cystic fibrosis and sickle cell anemia ?
Chapter 12 Solutions
Biology 2e
Ch. 12 - Figure 12.5 In pea plants, round peas (R) are...Ch. 12 - Figure 12.6 What are the genotypes of the...Ch. 12 - Figure 12.12 What ratio of offspring would result...Ch. 12 - Figure 12.16 In pea plants, purple flowers (P) are...Ch. 12 - Mendel performed hybridizations by transferring...Ch. 12 - Which is one of the seven characteristics that...Ch. 12 - Imagine you are performing a cross involving seed...Ch. 12 - Consider a cross to investigate the pea pod...Ch. 12 - A scientist pollinates a true-breeding pea plant...Ch. 12 - The observable traits expressed by an organism are...
Ch. 12 - A recessive trait will be observed in individuals...Ch. 12 - If black and white true-breeding mice are mated...Ch. 12 - The ABO blood groups in humans are expressed as...Ch. 12 - In a mating between two individuals that are...Ch. 12 - If the allele encoding polydactyly (six fingers)...Ch. 12 - A farmer raises black and white chickens. To his...Ch. 12 - Assuming no gene linkage, in a dihybrid cross of...Ch. 12 - The forked line and probability methods make use...Ch. 12 - How many different offspring genotypes are...Ch. 12 - Labrador retriever's fur color is controlled by...Ch. 12 - Which of the following situations does not follow...Ch. 12 - Describe one of the reasons why the garden pea was...Ch. 12 - How would you perform a reciprocal cross for the...Ch. 12 - Mendel performs a cross using a true-breeding pea...Ch. 12 - Calculate the probability of selecting a heart or...Ch. 12 - The gene for flower position in pea plants exists...Ch. 12 - Use a Punnett square to predict the offspring in a...Ch. 12 - Can a human male be a carrier of red-green color...Ch. 12 - Why is it more efficient to perform a test cross...Ch. 12 - Use the probability method to calculate the...Ch. 12 - Explain epistatis in terms of its Greek-language...Ch. 12 - In Section 12.3, ''Laws of Inheritance," an...Ch. 12 - People with trisomy 21 develop Down’s syndrome....Ch. 12 - A heterozygous pea plant produces violet flowers...
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- 1a) Explain one autosomal pattern of Mendelian inheritance. 1b) Describe one example of a disorder caused by this pattern on inheritance.arrow_forwardPKU is an inherited disease caused by a recessive allele. If a woman and her husband, who are both carriers (heterozygotes) for the disorder, have three children, what is the probability of each of the following? a) All three children are of normal phenotype. b) All three children have the disease. c) Any 2 of the three children have the normal phenotype.arrow_forwardSuppose a woman who is a carrier of sickle-cell trait (making her a heterozygote) has children with a man who is totally healthy and does not carry the gene for sickle-cell trait at all. Which one of the following is true about their potential children? (Draw a Punnett square on scratch paper if it helps you.) A) None of their children will have sickle-cell disease. B) All of their children will have sickle-cell disease. C) All of the couple's children would be heterozygous carriers like the mother.arrow_forward
- iii and ivarrow_forwardHemophilia A is transmitted by an X-linked recessive gene.With an affected father, what is the probability that a childwill have the disease? With an affected father and a carriermother, what is the probability?arrow_forwardAnastasia was the youngest daughter of Czar Nicholas II of Russia. She had no known children, and her fate following the Bolshevik Revolution is unknown. What is the probability that she was a heterozygous carrier of the allele for hemophilia?arrow_forward
- The gene for polydactyly (P) is autosomal and dominant to normal fingers (p). Hemophilia is sex-linked and recessive (X h ). A man and his wife both of whom are polydactylous and have normal red blood cells have a child who is non-polydactylous and with hemophilia. What are their genotypes?arrow_forwardO. 2 Hemophilia A is an X-linked trait where blood clotting is affected due to a mutation in a clotting factor protein. Georgio has hemophilia and attends a support group where he meets Gbenga, who does not have the disease, but whose father has hemophilia. Her mother is not affected. A) If they marry, what percentage % of all their children will have hemophilia? % B) Georgio meets another woman, Maria, at the hemophilia support group. Maria also lacks the trait, but her mother has hemophilia while her father is unaffected. # 3 Would a Georgio-Maria mating provide a larger chance of having afflicted children compared to a Georgio-Gbenga mating? C) Show how you came up with your answer to B. Edit View Insert Format Tools Table 12pt ✓ 80 F3 V Paragraph ✓ $ 4 Yes or No 000 000 F4 DO LO % 5 BIUAV T² | F5 ^ MacBook Air 6 2 F6 V & 7 F7 * 8 DII F8 ( 9 DD F9 1 0 S Farrow_forwardIn a woman who is a carrier of a mutant OTC deficiency allele, her sons who receive the mutant allele will be affected and her daughters will be carriers who may or may not be symptomatic, depending on random X inactivation in the liver. 1) Is this a single gene inheritance or multifactorial disease? 2) Is there a strong genetic or environmental cause to the development of this disease? If both genetic and environmental causes are implicated, you have to indicate each of them separately.arrow_forward
- varrow_forwardIn a multigenerational study of a family, 8% of the males and 8% of the females have red hair. What may be the cause of this? A)Autosomal inheritance B)Environmental influence C)Sex-linked inheritance D)Non-somatic inheritancearrow_forwardAn allele responsible for Marfan syndrome Section 13.4 is inherited in an autosomal dominant pattern. What is the chance that a child will inherit the allele if one parent does not carry it and the other is heterozygous?arrow_forward
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