Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 12, Problem 33CTQ
People with trisomy 21 develop Down’s syndrome. What law of
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Cystic Fibrosis (CF) is an autosomal recessive condition. Therefore, heterozygous (Cc) carriers do not display symptoms. Two parents who are carriers plan to start a family and you are a genetic counselor helping to advise them about their chances of having children affected by CF.
a) Suppose the couple has 4 children, each one year apart. What is the probability that all 4 children will inherit CF?
b) What is the probability that any 3 of their 4 children will not inherit CF, but 1 will be affected?
c) What is the probability that their first child will not inherit CF, but the younger 3 children will inherit CF?
Clara has polydactyly, an autosomal dominant that is 80% penetrant. Clara
inherited her polydactyly from her mother, her father had no polydactyly in his
family. She has an extra toe on her left foot. Her husband Ralph has no
polydactyly in his family.
A) What is the chance that Clara will have a child that will inherit polydactyly?
B) What is the chance that the child will express polydactyly.
You can leave these as un-calculated equations.
Cystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of sticky mucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helped the afflicted to live through adulthood.
Betty's mother died from cystic fibrosis, but her father was normal and never had any relative with CF. Her fiancé, Jones, turned out to be a carrier of the CF allele.
What are the genotypes of Betty and Jones?
1. Betty: ________________________
2. Jones: _____________________
They planned to have four children. What is the probability that:
3. all children will be normal
4. at least two will be normal
Chapter 12 Solutions
Biology 2e
Ch. 12 - Figure 12.5 In pea plants, round peas (R) are...Ch. 12 - Figure 12.6 What are the genotypes of the...Ch. 12 - Figure 12.12 What ratio of offspring would result...Ch. 12 - Figure 12.16 In pea plants, purple flowers (P) are...Ch. 12 - Mendel performed hybridizations by transferring...Ch. 12 - Which is one of the seven characteristics that...Ch. 12 - Imagine you are performing a cross involving seed...Ch. 12 - Consider a cross to investigate the pea pod...Ch. 12 - A scientist pollinates a true-breeding pea plant...Ch. 12 - The observable traits expressed by an organism are...
Ch. 12 - A recessive trait will be observed in individuals...Ch. 12 - If black and white true-breeding mice are mated...Ch. 12 - The ABO blood groups in humans are expressed as...Ch. 12 - In a mating between two individuals that are...Ch. 12 - If the allele encoding polydactyly (six fingers)...Ch. 12 - A farmer raises black and white chickens. To his...Ch. 12 - Assuming no gene linkage, in a dihybrid cross of...Ch. 12 - The forked line and probability methods make use...Ch. 12 - How many different offspring genotypes are...Ch. 12 - Labrador retriever's fur color is controlled by...Ch. 12 - Which of the following situations does not follow...Ch. 12 - Describe one of the reasons why the garden pea was...Ch. 12 - How would you perform a reciprocal cross for the...Ch. 12 - Mendel performs a cross using a true-breeding pea...Ch. 12 - Calculate the probability of selecting a heart or...Ch. 12 - The gene for flower position in pea plants exists...Ch. 12 - Use a Punnett square to predict the offspring in a...Ch. 12 - Can a human male be a carrier of red-green color...Ch. 12 - Why is it more efficient to perform a test cross...Ch. 12 - Use the probability method to calculate the...Ch. 12 - Explain epistatis in terms of its Greek-language...Ch. 12 - In Section 12.3, ''Laws of Inheritance," an...Ch. 12 - People with trisomy 21 develop Down’s syndrome....Ch. 12 - A heterozygous pea plant produces violet flowers...
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- What is heterozygote advantage. How does this phenomenon explain the preponderance of disorders such as cystic fibrosis and sickle cell anemia ?arrow_forwardFor the following diseases with their potential pedigree, mode of inheritance and the responsible gene: (Pedigrees A, B, and C) -> Do Pedigree C Pedigree B, Autosomal dominant, Huntingtin gene Pedigree B, Autosomal dominant, CFTR gene Pedigree B, Autosomal dominant, HexA gene Pedigree B, Autosomal dominant, FGFR3 gene Pedigree A, Autosomal recessive, CFTR gene Pedigree A, Autosomal recessive, Beta-globin gene Pedigree A, Autosomal dominant, FGFR3 gene Pedigree B, X-linked dominant. Factor VIII gene Pedigree A, Autosomal dominant, Beta-globin gene Pedigree A. Autosomal recessive, Huntingtin gene Pedigree C, X-linked recessive, Factor VIII gene Pedigree A, Autosomal recessive, HexA genearrow_forwardFor the following diseases with their potential pedigree, mode of inheritance and the responsible gene: (Pedigrees A, B, and C) -> Do Pedigree B Pedigree B, Autosomal dominant, Huntingtin gene Pedigree B, Autosomal dominant, CFTR gene Pedigree B, Autosomal dominant, HexA gene Pedigree B, Autosomal dominant, FGFR3 gene Pedigree A, Autosomal recessive, CFTR gene Pedigree A, Autosomal recessive, Beta-globin gene Pedigree A, Autosomal dominant, FGFR3 gene Pedigree B, X-linked dominant. Factor VIII gene Pedigree A, Autosomal dominant, Beta-globin gene Pedigree A. Autosomal recessive, Huntingtin gene Pedigree C, X-linked recessive, Factor VIII gene Pedigree A, Autosomal recessive, HexA genearrow_forward
- For the following diseases with their potential pedigree, mode of inheritance and the responsible gene: (Pedigrees A, B, and C) -> Do Pedigree A Pedigree B, Autosomal dominant, Huntingtin gene Pedigree B, Autosomal dominant, CFTR gene Pedigree B, Autosomal dominant, HexA gene Pedigree B, Autosomal dominant, FGFR3 gene Pedigree A, Autosomal recessive, CFTR gene Pedigree A, Autosomal recessive, Beta-globin gene Pedigree A, Autosomal dominant, FGFR3 gene Pedigree B, X-linked dominant. Factor VIII gene Pedigree A, Autosomal dominant, Beta-globin gene Pedigree A. Autosomal recessive, Huntingtin gene Pedigree C, X-linked recessive, Factor VIII gene Pedigree A, Autosomal recessive, HexA genearrow_forward1a) Explain one autosomal pattern of Mendelian inheritance. 1b) Describe one example of a disorder caused by this pattern on inheritance.arrow_forwardWhat is autosomal pattern of Mendelian inheritance.? What disorder is caused by this pattern on inheritance.arrow_forward
- The following pedigree follows the inheritance pattern of sickle cell anemia (b) in a family. What is the sex, genotype, and phenotype of individual II-5? 1 II 2 3 5 2 3 4 5 Unaffected female, Bb Unaffected male, bb Affected male, bb Affected female, Bb Unaffected male, BBarrow_forwardIs the sickle cell allele dominant or recessive? Explain. What is sickle cell trait?arrow_forwardPKU is an inherited disease caused by a recessive allele. If a woman and her husband, who are both carriers (heterozygotes) for the disorder, have three children, what is the probability of each of the following? a) All three children are of normal phenotype. b) All three children have the disease. c) Any 2 of the three children have the normal phenotype.arrow_forward
- Suppose a woman who is a carrier of sickle-cell trait (making her a heterozygote) has children with a man who is totally healthy and does not carry the gene for sickle-cell trait at all. Which one of the following is true about their potential children? (Draw a Punnett square on scratch paper if it helps you.) A) None of their children will have sickle-cell disease. B) All of their children will have sickle-cell disease. C) All of the couple's children would be heterozygous carriers like the mother.arrow_forwardiii and ivarrow_forwardA couple are both phenotypically normal but their son suffers from hemophilla, a sex linked recessive disorder. What fraction of their children are likely to suffer from hemophilia. what fraction are likely to be carriers.arrow_forward
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