Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
10th Edition
ISBN: 9780133922851
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 12, Problem 2TYU
Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to
- (A) disruption of mitotic spindle formation.
- (B) suppression of cyclin production.
- (C) myosin denaturation and inhibition of cleavage furrow formation.
- (D) inhibition of DNA synthesis.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Some cancer drugs stop cell division by stabilizing microtubules so they cannot come apart. Which step of the mitosis is disrupted?
A) Telophase
B) cytokinesis
C) Anaphase
D) Metaphase
Q49
. The decline of MPF activity at the end of mitosis is due to(A) the destruction of the protein kinase Cdk.(B) decreased synthesis of Cdk.(C) the degradation of cyclin.(D) the accumulation of cyclin.
Chapter 12 Solutions
Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
Ch. 12.1 - How many chromosomes are drawn in each part of...Ch. 12.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 12.2 - How many chromosomes are shown in the illustration...Ch. 12.2 - Compare cytokinesis in animal cells and plant...Ch. 12.2 - During which stages of the cell cycle does a...Ch. 12.2 - Compare the roles of tubulin and actin during...Ch. 12.2 - A kinetochore has been compared to a coupling...Ch. 12.2 - MAKE CONNECTIONS What other functions do actin...Ch. 12.3 - In Figure 12.14, why do the nuclei resulting from...Ch. 12.3 - How does MPF allow a cell to pass the G2 phase...
Ch. 12.3 - MAKE CONNECTIONS Explain how receptor tyrosine...Ch. 12 - Differentiate between these terms: chromosome,...Ch. 12 - In which of the three phases of interphase and the...Ch. 12 - Explain the significance of the G1, G2, and M...Ch. 12 - Through a microscope, you can see a cell plate...Ch. 12 - Vinblastine is a standard chemotherapeutic drug...Ch. 12 - One difference between cancer cells and normal...Ch. 12 - The decline of MPF activity at the end of mitosis...Ch. 12 - In the cells of some organisms, mitosis occurs...Ch. 12 - Which of the following does not occur during...Ch. 12 - Cell A has half as much DNA as cells B, C, and D...Ch. 12 - The drug cytochalasin B blocks the function of...Ch. 12 - VISUAL SKILLS The light micrograph shows dividing...Ch. 12 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 12 - EVOLUTION CONNECTION The result of mitosis is that...Ch. 12 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 12 - WRITE ABOUT A THEME: INFORMATION The continuity of...Ch. 12 - SYNTHESIZE YOUR KNOWLEDGE For selected answers,...
Additional Science Textbook Solutions
Find more solutions based on key concepts
How does trandlation differ from transcription?
Microbiology: Principles and Explorations
Explain why hyperthermophiles do not cause disease in humans.
Microbiology with Diseases by Taxonomy (5th Edition)
2. Why is it that the range of resting blood pressures of humans is best represented by a bell-shaped curve co...
Human Biology: Concepts and Current Issues
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Characterize the differences between tumor cells and normal cells in terms of the following properties. In cancer cells, how might each of these properties contribute to tumor progression? a) contact inhibition b) autocrine stimulation c) apoptosis d) senescence due to telomere shortening e) genomic stability f) angiogenises g) metastasisarrow_forwardA Patients with an inherited cancer have a mutation in a zinc-finger motif of P21 (a cell-cycle regulatory gene). Which of the following is the most likely result of this A) Decreased binding of a transcription factor to a DNA sequence B) Enhanced binding of hormones to receptors C) Enhanced transport of a hormone receptor complex into the nucleus D) Stimulation of mRNA synthesis E) "Unzipping" of leucine-rich helicesarrow_forward16)Tamoxifen acts as a ............. pharmaceutical agent: a)Estrogen receptor–blocking b)hormone therapy drug, is used to treat breast cancers c)Non–cell cycle active d)All choices e) both a and barrow_forward
- Which is true for cancer cells: 1) Cell death occurs after a determined number of cell divisions 2) Contact with other cells reduces chance of cell division 3) Cell division occurs in the presence of stop signals.arrow_forwardPart A and B A. What is the normal function of the Rb protein? A) Rb prevents the cell cycle from proceeding unless the cell is prepared to do so B) Rb causes cells to undergo apoptosis C) Rb promotes Cdk activation D) Each of the other selections is true E) Rb repairs damaged DNA B. How do tumors arise? A) When cell proliferation occurs at a higher rate than cell death B) When someone is infected with a tumor from another person C) When cell death occurs at a very high rate D) When cell proliferation occurs at a very low ratearrow_forwardWhich of the following regarding microtubules is LEAST correct? A)Microtubules do not have important functions in neurons B)Microtubules are important for anterograde axoplasmic transport C)No answer text provided. D)Microtubules are important for maintaining the structure of the neuron E)Microtubules are important for retrograde axoplasmic transportarrow_forward
- Biopsies from aggressive cancers often have cells that contain several nuclei per cell when viewed through a microscope. Which scenario could explain how such a multinucleated cell might have come to be? (a) The cell underwent repeated mitosis with simultaneous cytokinesis. (b) The cell had multiple S phases before it entered mitosis. (c) The cell underwent repeated mitosis, but cytokinesis did not occur. (d) The cell underwent repeated cytokinesis but no mitosis. (e) The cell actually went through meiosis and not mitosis.arrow_forwardGrowth factors induce synthesis of cyclin D and then Cyclin D promotes Cdk4 and Cdk6 which progress the cell from G1 to S phase. a) True b) Falsearrow_forwardTelophase in Mitosis a ) Chromosomes begin to uncoil into chromatin. b) Nucleolus and nuclear membrane begin to reappear. c) Spindle slowly dissolves. d) In animal cells, cytokinesis occurs with a cleavage furrow dividing one cell into two cells. e) In plant cells, cytokinesis occurs with the formation of a cell plate. This plate divides the original cell into two cells and is part of the new cell wall.arrow_forward
- Cytokinesis in plant cells is different than cytokinesis in animal cells. a) Explain why it has to be different, andb) briefly describe the processes in the two different cell types.arrow_forwardSpindle fibres first start to form during a) telophase. b) anaphase. c) metaphase. d) prophase.arrow_forward12) Match the cell-cell junction on the left with the appropriate function on the right. Note that more than one letter may apply for a particular function and that each letter may be used more than once or not at all. A) Gap junctions provides a very strong attachment point between cells B) Desmosomes allow easy movement of large amounts of substances between adjacent cells C) Plasmodesmata seals the plasma membranes of adjacent cells together, preventing the movement of molecules between them D) Tight junctionsarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
What are Mutations and what are the different types of Mutations?; Author: Science ABC;https://www.youtube.com/watch?v=I16YlE8qTBU;License: Standard youtube license