Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
10th Edition
ISBN: 9780133922851
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Textbook Question
Chapter 12, Problem 12.3CR
Explain the significance of the G1, G2, and M Checkpoints and the go-ahead signals involved in the cell cycle control system.
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Name at least one type of external stimulus that promotes re-entry of the cell cycle from G0 to G1 and signals to pass through the G1/S checkpoint.
Describe the three most important cell cycle checkpoints. Explain in a detailed manner and provide some sample scenarios.
Describe the general conditions that must be met at each of the three main cell-cycle checkpoints.
Chapter 12 Solutions
Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
Ch. 12.1 - How many chromosomes are drawn in each part of...Ch. 12.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 12.2 - How many chromosomes are shown in the illustration...Ch. 12.2 - Compare cytokinesis in animal cells and plant...Ch. 12.2 - During which stages of the cell cycle does a...Ch. 12.2 - Compare the roles of tubulin and actin during...Ch. 12.2 - A kinetochore has been compared to a coupling...Ch. 12.2 - MAKE CONNECTIONS What other functions do actin...Ch. 12.3 - In Figure 12.14, why do the nuclei resulting from...Ch. 12.3 - How does MPF allow a cell to pass the G2 phase...
Ch. 12.3 - MAKE CONNECTIONS Explain how receptor tyrosine...Ch. 12 - Differentiate between these terms: chromosome,...Ch. 12 - In which of the three phases of interphase and the...Ch. 12 - Explain the significance of the G1, G2, and M...Ch. 12 - Through a microscope, you can see a cell plate...Ch. 12 - Vinblastine is a standard chemotherapeutic drug...Ch. 12 - One difference between cancer cells and normal...Ch. 12 - The decline of MPF activity at the end of mitosis...Ch. 12 - In the cells of some organisms, mitosis occurs...Ch. 12 - Which of the following does not occur during...Ch. 12 - Cell A has half as much DNA as cells B, C, and D...Ch. 12 - The drug cytochalasin B blocks the function of...Ch. 12 - VISUAL SKILLS The light micrograph shows dividing...Ch. 12 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 12 - EVOLUTION CONNECTION The result of mitosis is that...Ch. 12 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 12 - WRITE ABOUT A THEME: INFORMATION The continuity of...Ch. 12 - SYNTHESIZE YOUR KNOWLEDGE For selected answers,...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What are the most important steps in cell-cycle regulation? Give some explanations and present some factors leading to uncontrolled cell cycle.arrow_forwardDescribe how p53 functions to arrest cells in G1 and G2 stages of the cell cycle to regulate the progression to the S and M stages respectivelyarrow_forwardThe Rb protein has been called the “master brake” of the cell cycle. Describe how the Rb protein acts as a cell cycle brake. How is the brake released in mid- to late G1 to allow the cell to proceed to S phase?arrow_forward
- Briefly explain the check-points of the cell cycle.arrow_forwardDescribe the purpose of cell cycle checkpoints.arrow_forwardWhat aspects of the cell cycle are controlled by the G1, G2, and M checkpoints? How are cyclins and cyclin-dependent protein kinases involved in cell cycle regulation at checkpoints?arrow_forward
- Explain in detail how phosphorylation of retinoblastoma (rb) protein leads to transition of the cell cycle from the G1 phase to the S phase. Be sure to include the role of all relevant accessory proteins, cylcins and CDK’sarrow_forwardExplain how cyclin and cyclin-dependent kinases control the cell cycle.arrow_forwardExplain Cyclin-dependent kinases (CDKs) control the cell cycle by phosphorylating other proteins?arrow_forward
- Review Figure 12.16 on cell cycle control. Would you expect MPF (maturation-promoting factor) activity to remain steady during cleavage? Explain.arrow_forwardWhat cellular mechanism(s) ensure that passage through the cell cycle is unidirectional and irreversible? What molecular machinery underlies these mechanism(s)?arrow_forwardA. Name the two proteins that induce a negative feedback in this pathway and explain why both feedback mechanisms exist? B. Discuss how a mutation resulting in an aberrant protein could cause changes in the cell cycle leading to uncontrolled cell division. Explain what the effect of the mutation would be on the protein’s function and what the effect will be on downstream proteins leading to enhanced cell cycle progressionarrow_forward
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