ANATOMY & PHYSIOLOGY LL W/CONNECT ACCESS
4th Edition
ISBN: 9781265521363
Author: McKinley
Publisher: MCG
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Question
Chapter 12, Problem 19DYKB
Summary Introduction
To explain:
The mechanism for the release of neurotransmitter from the synaptic knob.
Concept introduction:
Neurotransmitters are chemical substances which are released by the axon terminals when nerve impulses arrive. These neurotransmitters are stored in synaptic vesicles. These vesicles then fuse with the sending membrane which results in the release of neurotransmitter into the synaptic cleft.
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Discuss the different mechanisms for removing neurotransmitter from the synaptic cleft.
Discuss the steps that lead from the action potential arriving in the synaptic terminal to the release of neurotransmitter from synaptic vesicles.
Describe the molecular machinery required for neurotransmitter release at the synapse
Chapter 12 Solutions
ANATOMY & PHYSIOLOGY LL W/CONNECT ACCESS
Ch. 12.1 - Prob. 1WDYLCh. 12.1 - Prob. 2WDYLCh. 12.1 - Prob. 3WDYLCh. 12.2 - Prob. 4WDYLCh. 12.2 - Prob. 5WDYLCh. 12.2 - Prob. 6WDYLCh. 12.2 - Prob. 7WDYLCh. 12.2 - Prob. 8WDYLCh. 12.3 - Prob. 9WDYLCh. 12.4 - If a person has a brain tumor, is it more likely...
Ch. 12.4 - Prob. 11WDYLCh. 12.4 - Prob. 12WDYLCh. 12.4 - Prob. 13WDYLCh. 12.5 - Prob. 14WDYLCh. 12.5 - Prob. 15WDYLCh. 12.6 - Prob. 16WDYLCh. 12.6 - Prob. 17WDYLCh. 12.7 - Prob. 18WDYLCh. 12.7 - Prob. 19WDYLCh. 12.7 - Prob. 20WDYLCh. 12.8 - How are EPSP and IPSP graded potentials...Ch. 12.8 - Prob. 22WDYLCh. 12.8 - How does depolarization and repolarization occur...Ch. 12.8 - Prob. 24WDYLCh. 12.8 - Prob. 25WDYLCh. 12.9 - Prob. 26WDYLCh. 12.9 - Prob. 27WDYLCh. 12.9 - Prob. 28WDYLCh. 12.10 - Prob. 29WDYLCh. 12.10 - Prob. 30WDYLCh. 12.10 - Prob. 31WDYLCh. 12.11 - Prob. 32WDYLCh. 12.11 - Prob. 33WDYLCh. 12 - Prob. 1DYKBCh. 12 - Prob. 2DYKBCh. 12 - Prob. 3DYKBCh. 12 - Prob. 4DYKBCh. 12 - Prob. 5DYKBCh. 12 - Prob. 6DYKBCh. 12 - _____ 7. An action potential is generated when...Ch. 12 - Prob. 8DYKBCh. 12 - Prob. 9DYKBCh. 12 - Prob. 10DYKBCh. 12 - What are the four structural types of neurons? How...Ch. 12 - Prob. 12DYKBCh. 12 - How does myelination differ between the CNS and...Ch. 12 - Describe the procedure by which a PNS axon may...Ch. 12 - Prob. 15DYKBCh. 12 - Prob. 16DYKBCh. 12 - Explain summation of EPSPs and IPSPs and the...Ch. 12 - Graph and explain the events associated with an...Ch. 12 - Prob. 19DYKBCh. 12 - Prob. 20DYKBCh. 12 - Prob. 1CALCh. 12 - Prob. 2CALCh. 12 - Prob. 3CALCh. 12 - Prob. 4CALCh. 12 - Sarah wants to call her new friend Julie and needs...Ch. 12 - Over a period of 6 to 9 months, Marianne began to...Ch. 12 - Prob. 2CSLCh. 12 - Prob. 3CSL
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- A chemical synapse is a type of synapse that occurs between two neurons and between a motor neuron and skeletal muscle fibers (i.e. at a Neuromuscular junction, NMJ). Compare and contrast the specific events that occur at chemical synapses at these two sites. Describe clearly how they are similar and how they are different, starting at the arrival of a nerve impulse at the pre-synaptic neuron and ending up with the changes observed at the postsynaptic membranes.arrow_forwardIdentify the structure highlighted in green: Synaptic cleft Motor end plate Presynaptic membranearrow_forwardArrange the events that occur during synaptic transmission. Use letters A-F to denote the correct sequence. Use the diagram on the right as a clue. Example: SENDING NEURON vescJes B 1. lon channel opens Synepto SYNAPSE 1. lon channel opens 2. Neurotransmitter is released into synaptic cleft SYNAPTIC CLEFT RECEMNG NEURC4 Neurotransmitter To us 3. Vesicle fuses with plasma membrane Jon chzn nels Neurotrensmitter Feptor Neurotrensmitter broen down zna selaesed 4. Neurotransmitter binds to receptor tOnS 5. Action potential arrives 辦 6. lon channel closesarrow_forward
- Which types of patch clamp technique should be used if you want to determine if a particular compound is influencing synaptic transmission presynaptically or post synaptically?arrow_forwardDraw a typical action potential (correctly label axis) and explain in words the roles of ion channels in generating the different phases of the action potential. (Extra credit: How would opening voltage gated calcium channels upon depolarization affect the shape of the action potential if they have a relatively slow inactivation rate?)arrow_forwardIf you increase the amount of neurotransmitter in the synaptic cleft, how would you expect the post-synaptic potential (PSP) to change? a) The PSP would be stronger b) The PSP would change from depolarizing to hyperpolarizing c) The PSP would not changearrow_forward
- Organize the following steps into the correct signal transmission across a synapse. 1. Neurotransmitter molecules diffuse across the synaptic cleft 2. Neurotransmitter molecules bind to postsynaptic neurotransmitter receptors 3. Synaptic vesicles release neurotransmitter molecules 4. Impulse reaches the synaptic knob of the presynaptic neuronarrow_forwardDescribe how neurotransmitter binding to receptors on apostsynaptic cell causes inhibition or excitation.arrow_forwarda)Explain how the presynaptic cell "knows" when to release its neurotransmitter into the synaptic cleft. b)Explain the difference between excitatory and inhibitory neurotransmitters in regards to their effect on the postsynaptic cell.arrow_forward
- When an impulse arrives at the synapse, the synaptic vesicles open and release neurotransmitters into the cleft within a thousandth of a second. Within another ten thousandth of a second, these molecules have diffused across the cleft and bound to receptor sites in the effector cell. In what two ways is transmission across a synapse terminated so that the neuron’s signal is concluded?arrow_forwardDescribe the steps including the roll of ion terminals in a neuronal action potentialarrow_forwardWhich of the following statements about action potentials and information transmission in the synaptic cleft is FALSE? 1. Action potentials determine the amount of neurotransmitters that are released into the synaptic cleft 2.Action potentials ultimately result in more calcium leaving the target cell at the postsynaptic membrane 3. Action potentials determine the duration that neurotransmitters are released into the synaptic cleft 4. Action potentials ultimately result in more calcium entering the neuron at the axon terminalarrow_forward
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