Foundations in Microbiology
9th Edition
ISBN: 9780073522609
Author: Kathleen Park Talaro, Barry Chess Instructor
Publisher: McGraw-Hill Education
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Chapter 11.3, Problem 16ELO
Summary Introduction
Introduction:
Over the past few years, irradiation has been used extensively for sterilization and disinfection of materials that are heat and chemical sensitive. They are used in various health, drug and food industries.
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 11 Solutions
Foundations in Microbiology
Ch. 11.1 - Prob. 1ELOCh. 11.1 - Prob. 2ELOCh. 11.1 - 3. Define and differentiate among the major terms...Ch. 11.1 - 4. Characterize the parameters of microbial death,...Ch. 11.1 - 5. Summarize what factors influence the...Ch. 11.1 - 6. Identify the targets of antimicrobial control...Ch. 11.1 - Prob. 1CYPCh. 11.1 - Prob. 2CYPCh. 11.1 - 3. Contrast various microbes and rate their...Ch. 11.1 - 4. Explain how the types and numbers of...
Ch. 11.1 - Prob. 5CYPCh. 11.1 - Prob. 6CYPCh. 11.1 - Prob. 7CYPCh. 11.1 - Prob. 8CYPCh. 11.1 - Prob. 9CYPCh. 11.2 - Prob. 7ELOCh. 11.2 - Prob. 8ELOCh. 11.2 - Prob. 9ELOCh. 11.2 - 10. Differentiate between thermal death point and...Ch. 11.2 - 11. Describe several moist heat methods and their...Ch. 11.2 - Prob. 12ELOCh. 11.2 - Prob. 13ELOCh. 11.2 - 9. What happens to microbes that encounter...Ch. 11.2 - 10. Summarize the nature, mode of action, and...Ch. 11.2 - 11. Explain the concepts of TDT and TDP, using...Ch. 11.2 - Prob. 13CYPCh. 11.2 - 13. How can the temperature of steam be raised...Ch. 11.2 - Prob. 15CYPCh. 11.2 - Prob. 16CYPCh. 11.2 - 16. Explain why desiccation and cold are not...Ch. 11.3 - Prob. 14ELOCh. 11.3 - 15. Differentiate between ionizing and nonionizing...Ch. 11.3 - Prob. 16ELOCh. 11.3 - Prob. 17ELOCh. 11.3 - Prob. 18CYPCh. 11.3 - Prob. 19CYPCh. 11.3 - 19. What are some advantages and disadvantages of...Ch. 11.3 - Prob. 21CYPCh. 11.3 - Prob. 22CYPCh. 11.4 - Prob. 18ELOCh. 11.4 - 19. Explain the desirable features of...Ch. 11.4 - 20. Describe the types of halogens, their modes of...Ch. 11.4 - 21. Identify the characteristics of phenolic...Ch. 11.4 - 22. Describe the characteristics of oxidizing...Ch. 11.4 - Prob. 23ELOCh. 11.4 - 24. Explain how detergents, soaps, and heavy...Ch. 11.4 - 22. Describe situations that require high-level...Ch. 11.4 - 23. What is the difference between a tincture and...Ch. 11.4 - Name one chemical for which the general rule that...Ch. 11.4 - 24. Define sterilant, and name the principal...Ch. 11.4 - 25. Summarize the chief forms and uses of chlorine...Ch. 11.4 - 26. What are the superior characteristics of...Ch. 11.4 - 27. What are the modes of action of alcohols and...Ch. 11.4 - 28. Why is hydrogen peroxide solution so effective...Ch. 11.4 - 29. Give the uses and disadvantages of the heavy...Ch. 11.4 - 30. What does it mean to say that a chemical has...Ch. 11.L1 - Prob. 1MCQCh. 11.L1 - Prob. 2MCQCh. 11.L1 - Prob. 3MCQCh. 11.L1 - Prob. 4MCQCh. 11.L1 - Prob. 5MCQCh. 11.L1 - Prob. 6MCQCh. 11.L1 - 7. The primary action of ______ heat is to ______....Ch. 11.L1 - Prob. 8MCQCh. 11.L1 - 9. Microbe(s) that is/are the target(s) of...Ch. 11.L1 - 10. Ionizing radiation like _________ removes...Ch. 11.L1 - Prob. 11MCQCh. 11.L1 - Prob. 12MCQCh. 11.L1 - Prob. 13MCQCh. 11.L1 - 14. A chemical with sporicidal properties is a....Ch. 11.L1 - 15. Silver sulfadiazine is used a. in antisepsis...Ch. 11.L1 - Prob. 16MCQCh. 11.L1 - Prob. 17MCQCh. 11.L1 - 1. How would one best describe the state of being...Ch. 11.L1 - Prob. 2CSRCh. 11.L1 - Prob. 3CSRCh. 11.L1 - Prob. 1WCCh. 11.L1 - Prob. 2WCCh. 11.L1 - 4. Think of three situations in which the same...Ch. 11.L1 - 5. Explain what features of endospores make them...Ch. 11.L1 - 6. Explain some of the problems involved in...Ch. 11.L1 - 7. The shelf life and keeping qualities of fruit...Ch. 11.L2 - 1. For each item on the following list, propose a...Ch. 11.L2 - Prob. 2CTCh. 11.L2 - 3. It may seem contradictory that lyophilization...Ch. 11.L2 - 4. A supermarket/drugstore assignment: Look at the...Ch. 11.L2 - 5. Devise an experiment that will differentiate...Ch. 11.L2 - 6. There is quite a bit of concern that chlorine...Ch. 11.L2 - 7. Was the source patient in the case study most...Ch. 11.L2 - Prob. 8CTCh. 11.L2 - From chapter 2, figure 2.20. Study this...Ch. 11.L2 - 2. Explain what is happening with this graph that...
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