Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 11, Problem 6P

The enzyme micrococcal nuclease can cleave phosphodiester bonds on single- or double-stranded DNAs, but DNA that is bound to proteins is protected from digestion by micrococcal nuclease. When chromatin from eukaryotic cells is treated for a short period of time with micrococcal nuclease and then the DNA is extracted and analyzed by electrophoresis and ethidium bromide staining, the pattern shown in lane A on the following gel is found. Treatment for a longer time results in the pattern shown in lane B, and treatment for yet more time yields that shown in lane C. Interpret these results.

Chapter 11, Problem 6P, The enzyme micrococcal nuclease can cleave phosphodiester bonds on single- or double-stranded DNAs,

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