Campbell Biology (10th Edition)
10th Edition
ISBN: 9780321775658
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Textbook Question
Chapter 11, Problem 3TYU
Lipid-soluble signaling molecules, such as aldosterone, cross the membranes of all cells but affect only target cells because
(A) only target cells retain the appropriate DNA segments.
(B) intracellular receptors are present only in target cells.
(C) only target cells have enzymes that break down aldosterone.
(D) only in target cells is aldosterone able to initiate the phosphorylation cascade that turns genes on.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
1) Amino acids that contain hydroxyl groups in their R-groups can be phosphorylated during cellular signaling.
(a) What amino acids can be phosphorylated? (use the one letter amino acid abbreviations)
(b) Does phosphorylation turn a signaling protein “on” or “off”?
(c) Whatis the most common source of a phosphate used to phosphorylate a protein
(d) What enzyme type (or category of enzymes)removes phosphates from proteins?
It is important for the cell to be able to terminate responses, and diminish responsiveness to prevent overstimulation. Cells have different mechanisms for this. One such mechanism is receptor down regulation.
a.) Down regulation describes a decrease in the availability of hormones or neurotransmitters that bind to receptors on the surface of target cells, making the cells less likely to be stimulated.
b.) Down regulation describes glycosylation of receptor proteins receptors on the surface of target cells in order to decrease the selectivity of ligand binding, making the cells less sensitive to a hormone or neurotransmitter.
c.) Down regulation describes a decrease in the number of receptors on the surface of target cells, making the cells less sensitive to a hormone or neurotransmitter.
Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium. They have an important role in vascular homeostasis. Endothelin activates G protein-coupled receptors (GPCRs) ETA or ETB on a target cell. Which subunit of heterotrimeric G protein is released when the receptor is activated?
a.) gamme
b.) beta
c.) alpha
Chapter 11 Solutions
Campbell Biology (10th Edition)
Ch. 11.1 - Explain how signaling is involved in ensuring that...Ch. 11.1 - In liver cells, glycogen Phosphorylase acts in...Ch. 11.1 - Prob. 3CCCh. 11.2 - Nerve growth factor (NGF) is a water-soluble...Ch. 11.2 - WHAT IF? What would the effect be if a cell made...Ch. 11.2 - MAKE CONNECTIONS How is ligand binding similar to...Ch. 11.2 - Prob. 4CCCh. 11.3 - What is a protein kinase, and what is its role in...Ch. 11.3 - When a signal transduction pathway involves a...Ch. 11.3 - What is the actual signal that is being transduced...
Ch. 11.3 - WHAT IF? If you exposed a cell to a ligand that...Ch. 11.4 - How can a targct cell's response to a single...Ch. 11.4 - WHAT IF? If two cells have different scaffolding...Ch. 11.4 - Prob. 3CCCh. 11.5 - Give an example of apoptosis during embryonic...Ch. 11.5 - WH AT IF? If apoptosis occurred when it should...Ch. 11 - What determines whether a cell responds to a...Ch. 11 - How are the structures of a GPCR and an RTK...Ch. 11 - What is the difference between a protein kinase...Ch. 11 - What mechanisms in the cell terminale its response...Ch. 11 - What is an explanation for the similarities...Ch. 11 - Binding of a signaling molecule to which type of...Ch. 11 - The activation of receptor tyrosinc kinases is...Ch. 11 - Lipid-soluble signaling molecules, such as...Ch. 11 - Consider this pathway: epinephrine G...Ch. 11 - Apoptosis involves all but which of the following?...Ch. 11 - Which Observation suggestcd to Sutherland the...Ch. 11 - Protein phosphorylation is commonly involved with...Ch. 11 - DRAW IT Draw the following apoptotic pathway,...Ch. 11 - EVOLUTION CONNECTION Identify the evolutlonary...Ch. 11 - Prob. 10TYUCh. 11 - SCIENCE, TECHNOLOGY, AND SOCIETY The aging process...Ch. 11 - WRITE ABOUT A THEME: ORGANIZATION The properties...Ch. 11 - SYNTHESIZE YOUR KNOWLEDGE There are five basic...
Additional Science Textbook Solutions
Find more solutions based on key concepts
6. How can you use the features found in each chapter?
Human Anatomy & Physiology (2nd Edition)
Some people consider Pasteur or Koch to be the Father of Microbiology, rather than Leeuwenhoek. Why might they ...
Microbiology with Diseases by Body System (5th Edition)
Why is it necessary to be in a pressurized cabin when flying at 30,000 feet?
Anatomy & Physiology
Sea turtles have disappeared from many regions, and one way of trying to save them is to reintroduce them to ar...
MARINE BIOLOGY
What are the cervical and lumbar enlargements?
Principles of Anatomy and Physiology
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Please give the answers onlyarrow_forwardThe receptors for lipid-soluble signaling molecule, such as steroid hormones, are located: A) in the nucleus of the target cell B) in the cytoplasm of the target cell C) in the bloodstream D) inserted into the membrane of the target cell E) Lipid-insoluble hormones do not need receptorsarrow_forwardWhich of the following statements is true? Question 2 options: a) All cells will respond to the hormonal signal because hormones are broadcast throughout the body. b) The regulation of inflammatory responses at the site of an infection is an example of paracrine signaling. c) Paracrine signaling involves the secretion of stimuli into the bloodstream for distribution throughout the organism. d) The axons of neurons typically signal target cells using membrane-bound signaling molecules that act on receptors in the target cells.arrow_forward
- Signaling by tyrosine kinase receptors is generally associated with all of the following except: A) receptor dimerization B) growth factor responses C) heterotrimeric G proteins D) cross phosphorylation E) generating protein binding sites due to phosphorylationarrow_forwardIn intercellular signaling pathways, some receptor proteins can also act as a transcription factor (changing gene expression), because these receptors are ________. A) Group of answer choices B) Intracellular receptors C) Membrane bound receptors D) G protein coupled receptors E) Enzyme linked receptors F) Fast ligand-gated ion channelsarrow_forwardAn extracellular signaling molecule binds to cell surface receptor. This cell surface receptor changes shape and activates a trimeric G-protein. What kind of receptor is this? a) Ion-channel coupled receptor b) Receptor Tyrosine Kinase c) G-Protein coupled receptor d) All of the other answers are correct e) Enzyme-coupled receptorarrow_forward
- Although insulin initially acts through a tyrosine kinase receptor it also subsequently results in activation of a Ser/Thr protein kinase. Which one? A) Protein kinase A B) Protein kinase B C) Protein kinase C D) Ras E) Phosphoinositide-3-kinasearrow_forwardComparing cells synthesizing secretory proteins and cells secreting steroid hormones, the cells synthesizing the steroid hormones have: A) more rough ER. B) more smooth ER C) equal amounts of smooth and rough ER D) equal amounts of smooth and rough ER, but more lysosomes. E) equal amounts of smooth and rough ER, but fewer lysosomes.arrow_forwardWhen a chemical signal binds to an intracellular receptor ... a) ... it leads to the activation of G proteins. b) ... causes the receptor-hormone complex to open or close ion channels. c) ... the cell reacts faster than when a chemical signal binds to membrane-bound receptors. d) ... it leads to the formation of mRNA. e) ... the chemical signal is usually a large, water-soluble molecule.arrow_forward
- Signaling by tyrosine kinase receptors is generally associated with all of the following except: OA) receptor dimerization B) growth factor responses C) heterotrimeric G proteins OD) cross phosphorylation E) generating protein binding sites due to phosphorylationarrow_forwardQ30arrow_forwardSignaling molecules interact with cells through specific macromolecular receptors. For each of the four receptors identified below, list all characteris- tics, by number, which accurately describe that receptor. (a) An adrenergic receptor (b) A steroid receptor (c) The LDL receptor. (d) The insulin receptor, (1) Located at the cell surface (2) Associated with the protein clathrin (3) Ligand binding stimulates the activity of phospholipase C (4) A transmembrane protein (5) A DNA-binding protein (6) Located in the cell interior (7) Receptor-ligand complex moves to the lysosome (8) Receptor-ligand complex becomes concentrated in the nucleus (9) Receptor activation can inhibit the synthesis of glycogen (10) The hormone-receptor complex activates specific gene transcription (11) Internalization decreases the synthesis of cholesterol estersarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Great Glands - Your Endocrine System: CrashCourse Biology #33; Author: CrashCourse;https://www.youtube.com/watch?v=WVrlHH14q3o;License: Standard Youtube License