HeLa Cells Are a Genetic Mess HeLa cells can vary in chromosome number. Defects in proteins that orchestrate cell division result in descendant cells with too many or too few chromosomes, an outcome that is one of the ha1lmarks of cancer cells. The panel of chromosomes in FIGURE 11.9, originally published in 1989, shows all of the chromosomes in a single metaphase HeLa cell.
FIGURE 11.9 Karyotype of HeLa showing chromosomes in one cell.
How many extra chromosomes does this cell have, compared to a normal human body cell?
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- HeLa Cells Are a Genetic Mess HeLa cells can vary in chromosome number. Defects in proteins that orchestrate cell division result in descendant cells with too many or too few chromosomes, an outcome that is one of the ha1lmarks of cancer cells. The panel of chromosomes in FIGURE 11.9, originally published in 1989, shows all of the chromosomes in a single metaphase HeLa cell. FIGURE 11.9 Karyotype of HeLa showing chromosomes in one cell. Can you tell that this cell came from a female? How?arrow_forwardFigure 10.6 Which of the following is the correct order of events in mitosis? Sister chromatids line up at the metaphase plate. The kinetochore becomes attached to the mitotic spindle. The nucleus reforms and the cell divides. Cohesin proteins break down and the sister chromatids separate. The kinetochore becomes attached to the mitotic spindle. Cohesin proteins break down and the sister chromatids separate. Sister chromatids line up at the metaphase plate. The nucleus reforms and the cell divides. The kinetochore becomes attached to the cohesin proteins. Sister chromatids line up at the metaphase plate. The kinetochore breaks down and the sister chromatids separate. The nucleus reforms and the cell divides. The kinetochore becomes attached to the mitotic spindle. Sister chromatids line up at the metaphase plate. Cohesin proteins break down and the sister chromatids separate. The nucleus reforms and the cell divides.arrow_forwardThe figure below depicts cells from the same organism. Cell A is demonstrating which of the following: K J A Anaphase I Anaphase II O Anaphase of mitosis O Non-disjunction LLL B دے Carrow_forward
- The figure below shows the number of chromosomes observed in an actively dividing cell at each stage of cell division. A B number of chromsomes per cell C 100 90 D 80 A bar graph comparing the number of chromosomes at different stages of cell division. 20 Which of the following best explains the change in the number of chromosomes between metaphase and anaphase? prophase metaphase anaphase telophase cytokinesis stage of cell division New chromosomes formed during prophase are doubled during anaphase. DNA replication occurs between metaphase and anaphase, doubling the number of chromosomes. During metaphase, a cell contains identical copies of each chromosome, and then trans- forms into sister chromatids. During anaphase, the chromatids are separated, each becoming independent chromo- somes in its respective new cellarrow_forwardThe cells bellow are in the process and stages as indicated. Each cell has a 2n # of 6. In the cells below show all of the chromosomes and their proper location and draw and label the metaphase plate, kinetochore, spindle, centrosomes, homologous chromosomes, microtubules, DNA, sister chromatids, centromere MITOSIS (Metaphase) Total number of chromosomes Total number of homologous pairs of chromosomes MEIOSIS (Metaphase I)arrow_forwardA diploid organism has chromosomes. Use colours or symbols to show which chromosomes are which throughout each stage. Draw and label the chromosomes, sister chromatids, centromeres, spindle fibres, tetrad, crossing over and nucleus where appropriate. Prophase I Metaphase I Anaphase I Telophase I Prophase II Metaphase II Anaphase II Telophase II O曲T回A@ 28 Ai MacBook Pro K 2$ & 2 3 E R Y D F G K V B M command MOSISO commandarrow_forward
- Please help me explain this thank youarrow_forwardMatch the following to the descriptions provided.arrow_forwardThe genes below have been knocked out (loss of function). Draw what the cell would look like during the appropriately affected stage of mitosis. State what stage you are depicting on your drawing. (Each gene knockout is occurring in a different cell; you should have a drawing of the affected cell for each). 1. Separase, 2. Cohesinarrow_forward
- What are the stages of mitosis Chromatid doublets seperate to individual chromosomes. Centriole replicates Replicated chromosomes are arranged in single file net to another at the cell's equator.arrow_forwardWhich statements are true for mitosis? Group of answer choices (pick all that apply) 1. produces identical daughter cells 2. involved in sexual reproduction 3. reduces the number of chromosomes 4. involved in general growth and repair or asexual reproduction 5. produces cells that are almost always genetically different 6. produces diploid somatic cells 7. produces haploid gametesarrow_forwardDuring cell division, one of the daughter cells ended up with one more chromosome than the other daughter cell. A complication in what phase could have initiated this predicament? O prophase O anaphase O metaphase S Phasearrow_forward
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