Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN: 9781305073951
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 11, Problem 11SQ
Summary Introduction
Introduction: BRCA1 and BRCA2 are the two human genes normally expressed in the cells of breast and other tissue. Actually, BRCA is an abbreviation for breast cancer gene. This gene normally plays a big role in preventing breast cancer. They help to repair DNA breaks that can lead to cancer and the uncontrolled growth of tumors.
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A mutated gene that codes for an altered version of Cdk that is active in the absence of cyclin is a(n) _____. a. kinase inhibitor. b. tumor suppressor gene. c. proto-oncogene. d. oncogene.
Match the gene on the left with the gene category on the right.
ERBB2
E-cadherin
BRCA1
Cdk4
A.
oncogene
B.
proto-oncogene
C.
low expression in invasive cells
D.
tumor suppressor gene
A tumor suppressor gene ___regulates the cell cycle; an example is _____.
Select one:
a.
negatively, cyclin
b.
positively, retinoblastoma
c.
positively, p21
d.
negatively, retinoblastoma
e.
positively, RAS
Chapter 11 Solutions
Biology: The Unity and Diversity of Life (MindTap Course List)
Ch. 11 - HeLa Cells Are a Genetic Mess HeLa cells can vary...Ch. 11 - HeLa Cells Are a Genetic Mess HeLa cells can vary...Ch. 11 - HeLa Cells Are a Genetic Mess HeLa cells can vary...Ch. 11 - Prob. 1SQCh. 11 - A duplicated chromosome has how many chromatids?Ch. 11 - Prob. 3SQCh. 11 - Most cells spend the majority of their lives in...Ch. 11 - The spindle attaches to chromosomes at the...Ch. 11 - Only _______ is not a stage of mitosis. a....Ch. 11 - In intervals of interphase, G stands for ______....
Ch. 11 - Interphase is the part of the cell cycle when...Ch. 11 - After mitosis the chromosome number of a...Ch. 11 - Prob. 10SQCh. 11 - Prob. 11SQCh. 11 - Prob. 12SQCh. 11 - Match each term with its best description. __ cell...Ch. 11 - Prob. 14SQCh. 11 - When a cell reproduces by mitosis and cytoplasmic...Ch. 11 - The eukaryotic cell at left is in the process of...Ch. 11 - Exposure to radioisotopes or other sources of...Ch. 11 - Suppose you have a way to measure the amount of...
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- Cancer causing genes are called ________. a. transformation genes b. tumor suppressor genes c. oncogenes d. mutated genesarrow_forwardIn a simple sentence, can youarrow_forwardWhich of the following is typical of cancer cells? A. The parent cell of the tumor contains a single mutation in a single checkpoint gene. B. Malignant cells migrate. C. Cancer cells lose the ability to divide. D. Products of oncogenes inhibit mitosis E. Benign tumors invade normal tissue.arrow_forward
- An individual can inherit a gene in which expression has been altered by an ________ change with no mutation of the gene sequence. Choose the description in column 2 that best matches each gene in column 1. p53 c-myc A. tumor suppressor gene B. oncogenearrow_forwardA gene that codes for a positive cell-cycle regulator is called a(n) _____. a. kinase inhibitor. b. tumor suppressor gene. c. proto-oncogene. d. oncogene.arrow_forwardg protein D. Growth factor receptor ng Tool 0 Q ing C. Growth factor-binding protein D. Growth factor receptor E. Transcription activator A child with retinoblastoma is found to have a 13q14 deletion. The Rb gene, which resides at this locus, produces which kind of tumor-associated protein? A. Cell cycle regulator B. Growth factor ㅂ분 요 9 12 W □ @ 2 C Edit in Paint 8 60 8 Focusarrow_forward
- Tumor Suppressor Genes are often called as gatekeepers because: a. They signify their involvement in governing the dynamics of cell proliferation b. They allow tumors to proliferate at an uncontrolled rate c. To allow a transport channel of suppressors d. They are not referred to as ?gatekeepers?arrow_forwardHypermethylation is thought to contribute to cancer by a. inhibiting DNA replication. b. inhibiting the expression of tumor-suppressor genes. c. stimulating the translation of oncogenes. d. stimulating telomerase.arrow_forwardA tumor suppressor gene regulates the cell cycle; an example is . Select one: a. positively, p21 b. negatively, cyclin c. positively, retinoblastoma d. negatively, retinoblastoma e. positively, RAS Cycle HW due Jump to. 4) Next pa cancer stem cellsarrow_forward
- An oncogene is produced from a that has acquired a .a. proto-oncogene, loss-of-function mutationb. proto-oncogene, gain-of-function mutationc. tumor-suppressor gene, loss-of-function mutationd. tumor-suppressor gene, gain-of-function mutationarrow_forwardge Which of the following would most likely promote necrosis? Select one: a. activation of p53 b. pathogenic infection c. cyclin d. activation of cdk e. inactivation of p53 Cycle HW due Jump to... 46 Next page cancer stem cellsarrow_forwardA normally functioning gene that regulates the cell cycle by stopping cell division is most likely to be a(n) __________. Group of answer choices carcino-gene tumor suppressor proto-oncogene muta-gene oncogenearrow_forward
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