Biology: The Unity and Diversity of Life (MindTap Course List)
Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN: 9781305073951
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 11, Problem 11SQ
Summary Introduction

Introduction: BRCA1 and BRCA2 are the two human genes normally expressed in the cells of breast and other tissue. Actually, BRCA is an abbreviation for breast cancer gene. This gene normally plays a big role in preventing breast cancer. They help to repair DNA breaks that can lead to cancer and the uncontrolled growth of tumors.

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A mutated gene that codes for an altered version of Cdk that is active in the absence of cyclin is a(n) _____. a. kinase inhibitor. b. tumor suppressor gene. c. proto-oncogene. d. oncogene.
Match the gene on the left with the gene category on the right.                                                             ERBB2                                                             E-cadherin                                                             BRCA1                                                             Cdk4 A. oncogene B. proto-oncogene C. low expression in invasive cells D. tumor suppressor gene
A tumor suppressor gene ___regulates the cell cycle; an example is _____. Select one: a. negatively, cyclin b. positively, retinoblastoma c. positively, p21 d. negatively, retinoblastoma e. positively, RAS
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