Human Anatomy & Physiology (2nd Edition)
2nd Edition
ISBN: 9780134553511
Author: Erin C. Amerman
Publisher: PEARSON
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Chapter 10.2, Problem 6QC
Summary Introduction
To review:
Thetypesof functional proteinsthat are present in a myofibril.
Introduction:
A myofibril is also known as the muscle fiber. It is a rod-like structure and constitutes the basic unit of a muscle cell. The muscles contain tubular cells, which are called myocytes. In striated muscles, the tubular cells are known as the muscle fibers. The muscle fibers are made up of several chains of myofibrils.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 10 Solutions
Human Anatomy & Physiology (2nd Edition)
Ch. 10.1 - What are the two types of striated muscle?Ch. 10.1 - Which two types of muscle are involuntary?Ch. 10.1 - What is the basic function of all types of muscle...Ch. 10.1 - 4. What five properties are common to all muscle...Ch. 10.1 - Prob. 5QCCh. 10.2 - Prob. 1QCCh. 10.2 - How are the terminal cisternae related to the...Ch. 10.2 - Prob. 3QCCh. 10.2 - How does the arrangement of myofilaments produce...Ch. 10.2 - 5. Describe the structure of a sarcomere. What is...
Ch. 10.2 - Prob. 6QCCh. 10.2 - Describe the structures of thin filaments, thick...Ch. 10.2 - Prob. 8QCCh. 10.3 - What is the resting membrane potential?Ch. 10.3 - Prob. 2QCCh. 10.3 - 3. How do the electrochemical gradients for...Ch. 10.3 - What two factors generate the resting membrane...Ch. 10.3 - What is an action potential?Ch. 10.3 - What happens during the two phases of an action...Ch. 10.4 - Prob. 1QCCh. 10.4 - Prob. 2QCCh. 10.4 - 3. How does excitation from a neuron trigger...Ch. 10.4 - How are excitation and contraction coupled?Ch. 10.4 - What are the steps of the crossbridge cycle?Ch. 10.4 - Prob. 6QCCh. 10.5 - What are the two immediate energy sources for...Ch. 10.5 - How long can these immediate energy sources fuel...Ch. 10.5 - Prob. 3QCCh. 10.5 - Prob. 4QCCh. 10.5 - Prob. 5QCCh. 10.5 - Prob. 6QCCh. 10.5 - Prob. 7QCCh. 10.6 - What is a twitch contraction?Ch. 10.6 - What are the phases of a twitch contraction?Ch. 10.6 - How does the timing of a stimulus impact the...Ch. 10.6 - 4. How do fused and unfused tetanus differ?
Ch. 10.6 - 5. At what length will a sarcomere be able to...Ch. 10.6 - How do type I and type II muscle fibers differ?Ch. 10.7 - Prob. 1QCCh. 10.7 - 2. Explain the process of recruitment.
Ch. 10.7 - Prob. 3QCCh. 10.7 - 4. How do isotonic concentric, isotonic...Ch. 10.8 - Prob. 1QCCh. 10.8 - Prob. 2QCCh. 10.8 - Prob. 3QCCh. 10.8 - What conditions does excess postexercise oxygen...Ch. 10 - Mark the following statements as true or false. If...Ch. 10 - How does a skeletal muscle fiber differ...Ch. 10 - Thick filaments are composed of the protein a....Ch. 10 - Prob. 4CYRCh. 10 - Prob. 5CYRCh. 10 - Mark the following statements as true or false. If...Ch. 10 - Prob. 7CYRCh. 10 - 8. Order the following events of excitation and...Ch. 10 - 9. Which of the following statements accurately...Ch. 10 - 10. A muscle fiber relaxes when:
a. the...Ch. 10 - Which of the following energy sources would...Ch. 10 - 12. Mark the following statements as true or...Ch. 10 - Prob. 13CYRCh. 10 - 14. Muscle tone is:
a. the result of voluntary...Ch. 10 - Prob. 15CYRCh. 10 - Which of the following is not likely to result...Ch. 10 - Which of the following factors is/are responsible...Ch. 10 - 18. What is thought to cause excess postexercise...Ch. 10 - Prob. 19CYRCh. 10 - 20. Which of the following best describes...Ch. 10 - Mark the following statements as true for smooth...Ch. 10 - Prob. 1CYUCh. 10 - Prob. 2CYUCh. 10 - 3. The drug neostigmine blocks the activity of...Ch. 10 - Explain why cardiac muscle cells and some smooth...Ch. 10 - Prob. 1AYKACh. 10 - Prob. 2AYKACh. 10 - Prob. 3AYKACh. 10 - Prob. 4AYKACh. 10 - Prob. 5AYKBCh. 10 - Prob. 6AYKB
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