Jesse is 2 years old, presented with difficulty in walking and poor control of movements. His muscles are slow to relax and remain in the state of contraction even after movement is performed. Genetic analysis showed he is suffering from a genetic disorder that causes the pumps in the sarcoplasmic reticulum to work slower than normal speed. Characters in the case: Jesse has a genetic defect that makes sarcoplasmic reticulum slower. Adequate information: Jesse has difficulty in walking and poor control of movements. His muscles are slow to relax after movement is finished. He has a genetic defect that makes his sarcoplasmic reticulum slower. To determine: a. The defect in DNA leads to a malfunctioning protein. b. Jesse’s symptoms.

Question

Want to see the full answer?

Answer 1

Question

Chapter 10, Problem 6AYKB

Summary Introduction

Case summary:

Jesse is 2 years old, presented with difficulty in walking and poor control of movements. His muscles are slow to relax and remain in the state of contraction even after movement is performed. Genetic analysis showed he is suffering from a genetic disorder that causes the pumps in the sarcoplasmic reticulum to work slower than normal speed.

Characters in the case:

Jesse has a genetic defect that makes sarcoplasmic reticulum slower.

Adequate information:

Jesse has difficulty in walking and poor control of movements.

His muscles are slow to relax after movement is finished.

He has a genetic defect that makes his sarcoplasmic reticulum slower.

To determine:

a. The defect in DNA leads to a malfunctioning protein.

b. Jesse’s symptoms.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

19. On the diagram below a. Label the three pictures as: DNA; polypeptide; or RNA. b. Label the arrows as: translation or transcription/RNA processing. c. Add the following details to the diagram. Promoter region TATA box Transcription start site Transcription terminator Intron (A,B,C,D) Exons (1,2,3,4,5) Splice sites 5' cap 5' UTR (untranslated region) 3' poly A tail 3' UTR (untranslated region) Translational start (AUG) Translational stop (UGA, UAG, or UAA) N and C ends of polypeptide 0000

Match the letter labels in the figure below to the terms. Some letter labels are not used. MNNNNNNIN M C B A M D F E H K G 8

The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2