Seeley's Anatomy & Physiology
11th Edition
ISBN: 9780077736224
Author: Cinnamon VanPutte, Jennifer Regan, Andrew F. Russo Dr., Rod R. Seeley Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 10, Problem 5CT
When a person becomes Unconscious, the tongue muscles relax and the tongue tends o retract, or lull back, and obstruct the airway. Which tongue muscle is responsible? How can this be prevented or reversed?
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 10 Solutions
Seeley's Anatomy & Physiology
Ch. 10.1 - Distinguish between the origin and the insertion...Ch. 10.1 - Describe the roles of the following in muscle...Ch. 10.1 - Describe the different orientations of muscle...Ch. 10.1 - What geometric shapes can muscles have?Ch. 10.1 - List the criteria used to name muscles, and give...Ch. 10.1 - Using the terms fulcrum, lever, and force, explain...Ch. 10.1 - Describe the three classes of levers, and give on...Ch. 10.2 - Name the major movements of the head caused by...Ch. 10.2 - What is unusual about the insertion (and sometimes...Ch. 10.2 - Which muscles ore responsible for moving the ears,...
Ch. 10.2 - What usually causes ptosis on one side? Which...Ch. 10.2 - Name the muscles responsible for opening and...Ch. 10.2 - Prob. 13AYPCh. 10.2 - Contrast the movements produced by the extrinsic...Ch. 10.2 - Explain the interaction of the suprahyoid and...Ch. 10.2 - Prob. 16AYPCh. 10.2 - Describe the muscles of the eye and the movements...Ch. 10.3 - List the actions of the group of back muscles that...Ch. 10.3 - Prob. 19AYPCh. 10.3 - Explain the anatomical basis for the segments...Ch. 10.3 - What openings penetrate the pelvic diaphragm...Ch. 10.4 - Name the seven muscles that attach the scapula to...Ch. 10.4 - Prob. 23AYPCh. 10.4 - What muscles cause flexion and extension of the...Ch. 10.4 - Prob. 25AYPCh. 10.4 - Prob. 26AYPCh. 10.4 - Prob. 27AYPCh. 10.4 - Prob. 28AYPCh. 10.4 - Prob. 29AYPCh. 10.4 - Describe the muscles that move the thumb. The...Ch. 10.5 - Prob. 31AYPCh. 10.5 - Prob. 32AYPCh. 10.5 - Prob. 33AYPCh. 10.5 - What movement do the fibularis muscles nave in...Ch. 10.5 - Prob. 35AYPCh. 10.5 - Prob. 36AYPCh. 10 - Muscles that oppose one mother are a. synergists....Ch. 10 - The most movable attachment of a muscle is its a....Ch. 10 - The muscle whose name means it is to the side of...Ch. 10 - In a class III lever system, them a. fulcrum is...Ch. 10 - Prob. 5RACCh. 10 - An aerial circus performer who supports her body...Ch. 10 - Prob. 7RACCh. 10 - Prob. 8RACCh. 10 - The soft palate muscles a. prevent food from...Ch. 10 - Prob. 10RACCh. 10 - Prob. 11RACCh. 10 - Prob. 12RACCh. 10 - Prob. 13RACCh. 10 - Prob. 14RACCh. 10 - Prob. 15RACCh. 10 - Prob. 16RACCh. 10 - Which of these muscles is an antagonist of the...Ch. 10 - Prob. 18RACCh. 10 - Which of these muscles is an intrinsic hand muscle...Ch. 10 - Given these muscles: Iliopsoas Rectus femoris...Ch. 10 - Prob. 21RACCh. 10 - Prob. 22RACCh. 10 - The ________________ muscles evert the foot,...Ch. 10 - Prob. 24RACCh. 10 - For each of the following muscles: (1) describe...Ch. 10 - Consider only the effect of the brachioradialis...Ch. 10 - Prob. 3CTCh. 10 - Prob. 4CTCh. 10 - When a person becomes Unconscious, the tongue...Ch. 10 - Prob. 6CTCh. 10 - Savannah started a 200-meter dash and fell to the...Ch. 10 - Prob. 8CT
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