![Microbiology with Diseases by Body System (5th Edition)](https://www.bartleby.com/isbn_cover_images/9780134477206/9780134477206_largeCoverImage.gif)
To tell:
Why physicians do not invariably prescribe the antimicrobial with the largest zone of inhibition.
Introduction:
The disk-diffusion test is a method applied to evaluate the antibiotic susceptibility. In petri plate (where an antibiotic disk is placed on a uniformly inoculated test pathogen), the clear area (measured in diameter) showing the absence of bacterial growth is referred to as the zone of inhibition. The minimal inhibitory concentration (MIC) is the least antibiotic concentration required to inhibit visible growth of bacteria. The minimal bactericidal concentration (MBC) is the lowest concentration of antibiotic required to kill the bacteria. But, it cannot be used to determine whether an antibiotic is bactericidal or just bacteriostatic. In order to determine MIC and MBC of an antibacterial drug, a broth dilution test is useful.
![Check Mark](/static/check-mark.png)
Want to see the full answer?
Check out a sample textbook solution![Blurred answer](/static/blurred-answer.jpg)
Chapter 10 Solutions
Microbiology with Diseases by Body System (5th Edition)
- If your hospital laboratory isolates streptococcus pneumoniae from four patients on the same day, would you have to test the antimicrobial susceptibility of each isolate? Why or why not?arrow_forwardWhat are the major actions of antimicrobial agents? What criteria are used in the selection of antimicrobial agents?arrow_forwardWhat are the reasons for the failure of antimicrobial treatment?arrow_forward
- What is the purpose of the antimicrobial susceptibility test? What information can you gather from this method?arrow_forwardA newly admitted patient reports a penicillin allery. The prescriber has ordered a second-eneration cephalosporin as part of the therapy. Which nursin action is appropriate?a) Call the prescriber to clarify the order because of the patient’s allery.b )Give the medication, and monitor for adverse effects.c) Ask the pharmacy to chane the order to a first-eneration cephalosporin.d )Administer the dru with a nonsteroidal antiinflammatory dru to reduce adverse effectsarrow_forwardDistinguish between the antimicrobial effects of -static, -cidal,and -lytic agents.arrow_forward
- Explain what type of antimicrobial hand gels-alcohol or triclosan-you would recommend people use in their daily lives.arrow_forwardMany antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Tetracycline (ii) Puromycin (iii) Alpha-Amanitinarrow_forwardMany antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Chloramphenicol (ii) Rifamycinarrow_forward
- name two antimicrobials and explain whether the organism was susceptible, intermediate, or resistant.arrow_forwardWhat bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.arrow_forwardlist 4 families of antimicrobials that belong to the beta-lactam grouparrow_forward
- Essentials of Pharmacology for Health ProfessionsNursingISBN:9781305441620Author:WOODROWPublisher:Cengage