Microbiology with Diseases by Body System (5th Edition)
5th Edition
ISBN: 9780134477206
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Textbook Question
Chapter 10, Problem 1VI
Label each figure below to indicate the class of drug that is stopping polypeptide translation.
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Match the following antibiotics with the drug strategy that would provide resistance to
them.
rifampin which blocks transcription
[ Choose ]
Choose]
tetracycline which misaligns the
beta-lactamase
anticodon to its codon
mutation of the TRNA binding site of the ribosome
penicillin which blocks peptidoglycan
creation of alternate metabolic pathway that ultimately leads to the same product
synthesis
mutation of RNA polymerase
polymyxin which causes leakage in the
porin which removes drug from periplasmic space
cell membrane
sulfonamide which inhibits enzyme of
[Choose ]
folic acid synthesis pathway
Question 14
2 pts
%
&
5
7
Matching type
Choices are in the picture
1. Puromycin
2. Amanitin
3. Tetracycline
4. Rifampicin
5. Diphtheria Toxin
Choose the effect of the given agents to translation or transcription.
Choices:
RNA polymerase inhibition
RNA polymerase II inhibition
prevention of ribosomal movement in prokaryotes
disruption of elongation stage of translation
disruption of initiation stage of translation
prevention of ribosomal movement in eukaryotes
1. Rifampicin
2. Diptheria Toxin
3. Puromycin
4. Amanitin
5. Tetracycline
Chapter 10 Solutions
Microbiology with Diseases by Body System (5th Edition)
Ch. 10 - Prob. 1TMWCh. 10 - Some antimicrobial drugs are harmful to humans....Ch. 10 - Antibiotic Overkill A young woman was taking...Ch. 10 - Prob. 2CCSCh. 10 - Prob. 3TMWCh. 10 - Why is it incorrect to say that an individual...Ch. 10 - Prob. 1EDCSCh. 10 - Prob. 3CCSCh. 10 - Prob. 1MCCh. 10 - In a Kirby-Bauer susceptibility test, the presence...
Ch. 10 - Prob. 3MCCh. 10 - Prob. 4MCCh. 10 - Cross resistance is _____. a. the deactivation of...Ch. 10 - Prob. 6MCCh. 10 - Prob. 7MCCh. 10 - Prob. 8MCCh. 10 - Prob. 9MCCh. 10 - Prob. 10MCCh. 10 - Label each figure below to indicate the class of...Ch. 10 - What specific test for antimicrobial efficacy is...Ch. 10 - What characteristics would an ideal...Ch. 10 - Prob. 2SACh. 10 - Why is the fact that drug Z destroys the NAM...Ch. 10 - Given that both human cells and pathogens...Ch. 10 - Prob. 5SACh. 10 - Prob. 6SACh. 10 - Prob. 7SACh. 10 - Prob. 8SACh. 10 - Compare and contrast the actions of polyenes,...Ch. 10 - Prob. 10SACh. 10 - Prob. 1CTCh. 10 - How does Penicillium escape the effects of the...Ch. 10 - How might a colony of Bacillus licheniformis...Ch. 10 - Fewer than 1 % of known antibiotics have any...Ch. 10 - In an issue of News of the Lepidopterists Society,...Ch. 10 - Even though aminoglycosides such as gentamicin can...Ch. 10 - Prob. 7CTCh. 10 - Prob. 8CTCh. 10 - Why might amphotericin B affect the kidneys more...Ch. 10 - Antiparasitic drugs in the benzimidazole family...Ch. 10 - Prob. 11CTCh. 10 - Scientists have cultured bacteria isolated from...Ch. 10 - Prob. 13CTCh. 10 - Prob. 14CTCh. 10 - Enterococcus faecium is frequently resistant to...Ch. 10 - Prob. 1CM
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What are the important types MRNA molecule or genetic sequence that you can target to design a drug? Don't copy paste your answer from websites... Use your own answersarrow_forwardWhen choosing a "first line" drug to treat an infection, the most important characteristic would be? the specific mechanism of action bactericidal broad spectrum low toxicity (fewest side effects) In what cell type can both transcription and translation occur simultaneously? both prokaryotic and eukaryotic cells neither prokaryotic and eukaryotic cells prokaryotic cells eukaryotic cellsarrow_forwardIn this question you are explain in your own words, how RNA interference can be a therapeutic approach for the treatment of diseases. You may include a diagram to aid your explanation.arrow_forward
- Choose the effect of the given agents to translation or transcription. CHOICES: prevention of ribosomal movement in eukaryotes our email will be recorded when you submit thi prevention of ribosomal movement in prokaryotes RNA polymerase II inhibition RNA polymerase inhibition disruption of elongation stage of translation Tetracycline * Puromycin * Amanitin * Rifampicin * Diphtheria Toxin *arrow_forwardDiscuss two possible 'magic bullets' you have already learned about for targeting bacteria with drugs.arrow_forwardBriefly discuss RNA interference.arrow_forward
- A SNP that results in loss of all catalytic activity of a drug-metabolizing enzyme is most likely to occur in the codon for which of the following amino acids? Valine Phenylalanine Why? Correct Answer: Aspartatearrow_forwardFor the given mutation below,please write down the reverse mutation and any intragenic suppressor mutations for that mutation. Use the codon table for amino acids as reference. In this case, mutation means single letter change. Mutation: AGA -> AGC Arg codons: CGU, CGC, CGA, CGG,AGA,ACG Ser codons: UCU, UCC, UCA, UCG, AGU, AGC Character limit is 10 characters. Write down Reverse mutation sequence first and then intragenic suppressor mutation sequence. Write down the mutated sequence not the mutation.arrow_forwardSeveral common antibiotics affect some strains of bacteria's ability to carry out transcription and/or translation. For example: Rifamycin inhibits prokaryotic RNA polymerase Chloramphenicol blocks the transfer of the peptide from the P to A site. a) For each of these drugs, identify at what point it could affect the process of DNA->RNA->protein. Be as specific as possible. b) Why do you think these drugs kill bacteria but spare animal cells? (Hint: remember bacteria are prokaryotes)arrow_forward
- Please fill out the following table. Circle sense or template strands. Indicate 5’, 3’, amino and carboxy ends. Use wobble whenever possiblearrow_forwardUse the blanks on the left hand side to put the following statements in order (use numbers or letters to designate the order). All of the statements refer to the diauxic (sequential) growth of a bacterium on the carbon substrates glucose and lactose (see textbook Fig 4.11 on diauxic growth). Remember, the lac operon contains the genes necessary for the lactose catabolism. The glucose substrate is completely consumed, at which time the repressor protein on the lac operon unbinds from the DNA molecule. The lactose substrate is catabolized by the active B-galactosidase enzyme. Glucose, as the preferred carbon substrate, is first consumed by catabolic enzymes that are constitutive (always present). After completion of translation, the B-galactosidase enzyme undergoes folding to form into an active enzyme that can breakdown lactose into its constituent monosaccharides. The messenger RNA code from the lac operon is translated by ribosomal RNAS to form lac-related enzymes, such as…arrow_forwardWhat are the modifying factors and toxic/therapeutic effects of cisplatin? Define all new terms and acronyms. Please don't put AI/GPT text, please make sure all text is 100% human written Please include at least 5 reliable apa references.arrow_forward
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