Concept explainers
To review:
The regulatory mechanisms working at the DNA (deoxyribonucleic acid) level, transcriptional level, translational level, and post-translational level.
Introduction:
Gene expression is the process by which the information encoded in the genes is used to synthesize a functional gene product. This can be controlled at various levels such as the DNA level, transcriptional level, translational level, and post-translational stage. Regulation is required to decrease or increase the formation of specific proteins or RNA (ribonucleic acid).

Explanation of Solution
The regulatory mechanisms occurring at the DNA level are as follows:
1. Gene inversion on/off switch: In this mechanism, there is the flipping of orientation of a gene or segment of DNA in the chromosome.
2. Slipped strand-mispairing: It is a type of mutation process occurring at the time of replication of DNA. It results in the mispairing of complementary bases due to denaturation and displacement of DNA strands.
The regulatory mechanisms present at the transcriptional level are as follows:
1. Repressors and activators are present that interact with the DNA. Activators are responsible for complementing the functions of the enzymes involved in transcription while the repressors inhibit or suppress the transcription process.
2. The sRNAs (small RNAs) may attach to the mRNAs (messenger RNAs) and interfere with the activities of the RNases.
The best example of regulation at translational level is the attenuation process. It is a regulatory mechanism that is present in certain bacterial operons and leads to premature termination of the transcription process. The regulatory mechanisms at post-translation level include chemical modifications of the enzymes through the process of phosphorylation, methylation, acetylation, or cleavage. The modifications either enhance or reduce the activities of the enzymes.
Want to see more full solutions like this?
Chapter 10 Solutions
MICROBIOLOGY: EVOLV.SCI.-W/ACCESS>CI<
- Amino Acid Coclow TABle 3' Gly Phe Leu (G) (F) (L) 3- Val (V) Arg (R) Ser (S) Ala (A) Lys (K) CAG G Glu Asp (E) (D) Ser (S) CCCAGUCAGUCAGUCAG 0204 C U A G C Asn (N) G 4 A AGU C GU (5) AC C UGA A G5 C CUGACUGACUGACUGAC Thr (T) Met (M) lle £€ (1) U 4 G Tyr Σε (Y) U Cys (C) C A G Trp (W) 3' U C A Leu בוט His Pro (P) ££ (H) Gin (Q) Arg 흐름 (R) (L) Start Stop 8. Transcription and Translation Practice: (Video 10-1 and 10-2) A. Below is the sense strand of a DNA gene. Using the sense strand, create the antisense DNA strand and label the 5' and 3' ends. B. Use the antisense strand that you create in part A as a template to create the mRNA transcript of the gene and label the 5' and 3' ends. C. Translate the mRNA you produced in part B into the polypeptide sequence making sure to follow all the rules of translation. 5'-AGCATGACTAATAGTTGTTGAGCTGTC-3' (sense strand) 4arrow_forwardWhat is the structure and function of Eukaryotic cells, including their organelles? How are Eukaryotic cells different than Prokaryotic cells, in terms of evolution which form of the cell might have came first? How do Eukaryotic cells become malignant (cancerous)?arrow_forwardWhat are the roles of DNA and proteins inside of the cell? What are the building blocks or molecular components of the DNA and proteins? How are proteins produced within the cell? What connection is there between DNA, proteins, and the cell cycle? What is the relationship between DNA, proteins, and Cancer?arrow_forward
- please fill in the empty sports, thank you!arrow_forwardIn one paragraph show how atoms and they're structure are related to the structure of dna and proteins. Talk about what atoms are. what they're made of, why chemical bonding is important to DNA?arrow_forwardWhat are the structure and properties of atoms and chemical bonds (especially how they relate to DNA and proteins).arrow_forward
- The Sentinel Cell: Nature’s Answer to Cancer?arrow_forwardMolecular Biology Question You are working to characterize a novel protein in mice. Analysis shows that high levels of the primary transcript that codes for this protein are found in tissue from the brain, muscle, liver, and pancreas. However, an antibody that recognizes the C-terminal portion of the protein indicates that the protein is present in brain, muscle, and liver, but not in the pancreas. What is the most likely explanation for this result?arrow_forwardMolecular Biology Explain/discuss how “slow stop” and “quick/fast stop” mutants wereused to identify different protein involved in DNA replication in E. coli.arrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage LearningHuman Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningAnatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax College
- Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage LearningBiology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage LearningBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax





