
Concept explainers
(a)
Interpretation: Each double bond in lejimalide B is to be labeled as
Concept introduction: Stereochemistry is defined as the arrangement of molecule in three dimensional and its impact on
The use of prefix
(b)
Interpretation: Each tetrahedral stereogenic center in the given drug is to be labeled as
Concept introduction: Rules for assigning R and S configuration are as follows:
1. The groups are prioritized on the basis of their
2. If the atoms that are attached to the chiral centre are similar to each other, then the priority is given on the basis of the next atom attached.
3. The molecule is oriented in such a manner that the lowest priority group comes at the dashed wedge.
4. If the first three high priority groups are present in a clockwise manner then the molecule is assigned R configuration but if these are present in an anticlockwise manner then the molecule is assigned with S configuration.
(c)
Interpretation: The number of stereoisomers possible for lejimalide B is to be predicted.
Concept introduction: A compound exhibits number of stereoisomers when it contains more than one stereogenic centers. The maximum number of stereoisomers a compound with n number of stereogenic centers can show is

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Chapter 10 Solutions
PKG ORGANIC CHEMISTRY
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