You are investigating inhibitors of chymotrypsin, and the two molecules shown on the right (A&B) are being considered. Draw a Lineweaver-Burke plot showing the expected effect of each of these molecules on normal chymotrypsin kinetics. Indicate which molecule you would pick as the better inhibitor. You want to improve the inhibitor you selected above. Briefly describe one key change you could make to your molecule to make it a better inhibitor. Justify your answer
You are investigating inhibitors of chymotrypsin, and the two molecules shown on the right (A&B) are being considered. Draw a Lineweaver-Burke plot showing the expected effect of each of these molecules on normal chymotrypsin kinetics. Indicate which molecule you would pick as the better inhibitor. You want to improve the inhibitor you selected above. Briefly describe one key change you could make to your molecule to make it a better inhibitor. Justify your answer
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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You are investigating inhibitors of chymotrypsin, and the two molecules shown on the right (A&B) are being considered. Draw a Lineweaver-Burke plot showing the expected effect of each of these molecules on normal chymotrypsin kinetics. Indicate which molecule you would pick as the better inhibitor.
You want to improve the inhibitor you selected above. Briefly describe one key change you could make to your molecule to make it a better inhibitor. Justify your answer.
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