You are working for a drug discovery company. Your team has identified a derivative (you will be given a randomly selected compound from the table below) of aspirin/paracetamol, has optimal physicochemical properties for biological activity. To conduct preliminary tests on the drug candidate you are required to synthesise the derivative from benzene. Propose a synthetic pathway starting from benzene to the candidate drug. Important: your company wants efficiency, a synthetic, pathways that provide good yield (major product) and are energy efficient (if possible, avoid pathways that involve working with lots of ring deactivating groups) is preferred. H3CO. HO S
You are working for a drug discovery company. Your team has identified a derivative (you will be given a randomly selected compound from the table below) of aspirin/paracetamol, has optimal physicochemical properties for biological activity. To conduct preliminary tests on the drug candidate you are required to synthesise the derivative from benzene. Propose a synthetic pathway starting from benzene to the candidate drug. Important: your company wants efficiency, a synthetic, pathways that provide good yield (major product) and are energy efficient (if possible, avoid pathways that involve working with lots of ring deactivating groups) is preferred. H3CO. HO S
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![You are working for a drug discovery company. Your team has identified a derivative (you will
be given a randomly selected compound from the table below) of aspirin/paracetamol, has
optimal physicochemical properties for biological activity. To conduct preliminary tests on the
drug candidate you are required to synthesise the derivative from benzene. Propose a
synthetic pathway starting from benzene to the candidate drug.
Important: your company wants efficiency, a synthetic, pathways that provide good yield
(major product) and are energy efficient (if possible, avoid pathways that involve working with
lots of ring deactivating groups) is preferred.
H3CO
HO
O](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F82469b80-1cf8-4e6c-a988-89cb397843aa%2Fa739cb6e-ac47-419d-a3cc-e2579f637f4c%2Fyzmjllv_processed.jpeg&w=3840&q=75)
Transcribed Image Text:You are working for a drug discovery company. Your team has identified a derivative (you will
be given a randomly selected compound from the table below) of aspirin/paracetamol, has
optimal physicochemical properties for biological activity. To conduct preliminary tests on the
drug candidate you are required to synthesise the derivative from benzene. Propose a
synthetic pathway starting from benzene to the candidate drug.
Important: your company wants efficiency, a synthetic, pathways that provide good yield
(major product) and are energy efficient (if possible, avoid pathways that involve working with
lots of ring deactivating groups) is preferred.
H3CO
HO
O
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