Wild type 5' 3' Č G ĠŤÁ Ć Ġ Ť Ť Á Á À G C C ATG C A ATTT 3' DNA 5' Č Ġ G GUU A A A 3' Transcribed codons Arginine Tyrosine Valine Lysine Amino acids translated Mutant Base pair addition - 5'- 3' C G ĞÁŤ Á ČĠŤŤ Á Á Á GC C TATGC A ATT! DNA 3' iil5' TIIT 5' 3' Transcribed codons CGG Arginine Isoleucine Arginine STOP Amino acids translated FIGURE 8.4 Frameshift Mutation as a Result of Nucleotide Addition The addition of a nucleotide pair (base pair) to the DNA results in a shift in the reading frame when the sequence is transcribed and translated. Deletion of a single nucleotide pair in the DNA would have a similar effect.
Wild type 5' 3' Č G ĠŤÁ Ć Ġ Ť Ť Á Á À G C C ATG C A ATTT 3' DNA 5' Č Ġ G GUU A A A 3' Transcribed codons Arginine Tyrosine Valine Lysine Amino acids translated Mutant Base pair addition - 5'- 3' C G ĞÁŤ Á ČĠŤŤ Á Á Á GC C TATGC A ATT! DNA 3' iil5' TIIT 5' 3' Transcribed codons CGG Arginine Isoleucine Arginine STOP Amino acids translated FIGURE 8.4 Frameshift Mutation as a Result of Nucleotide Addition The addition of a nucleotide pair (base pair) to the DNA results in a shift in the reading frame when the sequence is transcribed and translated. Deletion of a single nucleotide pair in the DNA would have a similar effect.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
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Transcribed Image Text:Wild type
5'
3'
Č G ĠŤÁ Ć Ġ Ť Ť Á Á À
G C C ATG C A ATTT
3'
DNA
5'
Č Ġ G
GUU
A A A
3'
Transcribed codons
Arginine Tyrosine
Valine
Lysine
Amino acids translated
Mutant
Base pair
addition -
5'-
3'
C G ĞÁŤ Á ČĠŤŤ Á Á Á
GC C TATGC A ATT!
DNA
3'
iil5'
TIIT
5'
3'
Transcribed codons
CGG
Arginine Isoleucine Arginine
STOP
Amino acids translated
FIGURE 8.4 Frameshift Mutation as a Result of Nucleotide
Addition The addition of a nucleotide pair (base pair) to the DNA
results in a shift in the reading frame when the sequence is transcribed
and translated. Deletion of a single nucleotide pair in the DNA would
have a similar effect.
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