Why is p53 considered a tumor suppressor protein? Question 12 options: a) Because p53 normally detects breaks in DNA. b) Because p53 normally causes progression from G1 to S phase to halt until damaged DNA is fully repaired. c) Because p53 normally repairs breaks in DNA. d) Because p53 normally stimulates transcription of Repair Polymerase. e) Because p53 normally reduces the mutation rate of DNA polymerase.
Why is p53 considered a tumor suppressor protein?
Question 12 options:
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p53 is a tumor suppressor protein because it helps to prevent cells with damaged DNA from dividing. When DNA is damaged, p53 can halt the cell cycle at the G1/S checkpoint. This allows the cell to repair the DNA damage before proceeding to the next phase of the cell cycle. If the DNA damage is too severe to be repaired, p53 can induce apoptosis, or programmed cell death.
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