Why is DNA pol III still a thing, given that it lacks some of the functionality of DNA pol I - why hasn't it been lost/eliminated from cells?

Q: Please explain one type of “DNA repair” mechanism (what is it, when is it used, how does it work).

A: The process by which a cell detects and repairs damage to the DNA molecules that encode its genome…

Q: During DNA replication, both positive and negative supercoiling is introduced in the DNA being…

A: Loosening up of the helix during Deoxyribose Nucleic Acid (DNA) replication (by the activity of…

Q: Does the addition of a histidine tag affect DNA polymerase activity and or processivity? Give a…

A: DNA polymerase is an important enzyme of dna replication and can add nucleotide triphosphates to 3’…

Q: How many equivalents of ATP are required to replicate a 1000 bp stretch of DNA? B. If the incorrect…

A: Before an answer is given, the process of DNA replication must be understood. First there are two…

Q: Why can’t a linear duplex DNA, such as that of bacteriophage T7, be fully replicated by just E.…

A: There are two replication systems present in organisms, namely linear DNA replication system and…

Q: 1) What is Dna mutaion and its types

A: Mutation can be described as a heritable genetic change in the genetic material of an organism that…

Q: In denatured DNA, DNA double helix is disrupted, which causes the exposure of the bases and thus…

A: The correct option is the C option: In denatured DNA, DNA double helix is disrupted, which causes…

Q: A DNA template strand containing a thymine dimer can be replicated by DNA polymerase η. Does pol η…

A: Pyrimidine dimers are molecular lesions formed from thymine or cytosine bases in DNA via…

Q: E. coli DNA polymerase V has the ability to bypass thymine dimers. However, Pol V tends to…

A: DNA polymerase is an enzyme, which helps to synthesize new complementary strands with the…

Q: If DNA polymerase requires a perfectly pairedprimer in order to add the next nucleotide, how is it…

A: DNA polymerases are enzymes that manufacture DNA molecules by assembling nucleotides, which are the…

Q: explain the laws of DNA polymerase? Why are they important and are all the laws required for DNA…

A: DNA polymerase is the enzyme that is helpful in catalysing the DNA molecules synthesis. There are…

Q: Explain why base excision repair, nucleotide excision repair, and mismatch repair—which all require…

A: Mutations are changes that occurs in the deoxyribonucleic acid (DNA) sequence, either due to…

Q: Polymerases usually add only about 10 nucleotides to a DNA strand before dissociating. However,…

A: The DNA replication is carried out by an enzyme called as DNA polymerase enzyme that can only add…

Q: The binding of the SSB (single-stranded binding) protein with DNA (deoxyribonucleic acid) and still…

A: Only when both strands of DNA are been allows to  separated from one other can state the  DNA in the…

Q: Smoking status is a known risk factor for lung cancer development. Researchers are conducting a…

A:

Q: It was once thought that the DNA polymerase machinery moves along DNA in a manner analogous to a…

A: DNA polymerase is defined as the family of enzymes responsible for catalyzing the synthesis of new…

Q: All known DNA polymerases catalyze synthesis only in the 5' → 3' direction.  Nevertheless, during…

A: DNA replication is the process of making two identical copies of DNA. The process is carried by the…

Q: What does it mean to say that extensions by DNA polymerase III proceeds 5' to 3'?

A: DNA replication is a process through which a new copy of DNA is synthesized. DNA polymerase III is…

Q: Describe an experimental approach to determining the processivity of a DNA polymerase (i.e., the…

A: Processivity is the average number of bases a polymerase enzyme will extend and incorporate base…

Q: Consider the following segment of DNA, which is part of a linear chromosome: LEFT…

A: DNA replication is the process by which the DNA is copied in the cell to make up more number of DNA…

Q: Which travels the farthest shorter or larger fragments of DNA? Why?

A: The technique that is used for the separation of DNA based on its size is referred to as gel…

Q: Match the bold DNA repair response(s) to the triggering type of DNA damage. Homologous…

A: Homologous Recombination: Double-Strand Break repair mechanism which is an accurate repair mechanism…

Q: The epsilon subunit of DNA polymerase III is responsible for its _______ activity. A-5'---->3'…

A: DNA Polymerase III is an enzyme that is involved in DNA replication and synthesis. It has 3'-5'…

Q: A person with deficient or abnormal ligase may have an increased cancer risk and chromosome breaks…

A: Enzymes are essential biocatalysts for all living cells. Enzymes carry out various functions in the…

Q: In experiments using polymerase chain reactions (PCR), it is often more difficult to amplify through…

A: Introduction :- Polymerase Chain Reaction (PCR) is a laboratory technique used to make many copies…

Q: The original wild-type" DNA strand is: 5'-ATGGGACTAGATACC-3'. Which allele is least likely to show a…

A: A DNA mutation is a permanent change in the DNA sequence that can be passed on to subsequent…

Q: "The mechanism does not recruit a homologous region of DNA during repair". Explain this ?

A: Introduction DNA repair is a set of procedures that a cell uses to detect and repair damage to the…

Q: What is a true statement about the leading and lagging strands during DNA synthesis? The leading…

A: Ans : Correct statement for the above question is - The lagging strand is created due to DNA…

Q: a. Replicate this sense strand to create a double-stranded DNA helix. Write your answers in CAPS…

A: DNA replication is a phenomenon in which DNA make itself using Enzyme DNA Polymerase . It occurs in…

Q: 2b) Suppose you generated a mutant E. coli strain in which it was DNA Polymerase I that was…

A: "DNA polymerases are enzymes that catalyse DNA synthesis during replication." The primary function…

Q: Explain why it is necessary that DNA is replicated continuously on the leading strand by but…

A: Introduction :  Direction of DNA replication is 5' - 3' .  Primase add primer and DNA polymerase…

Q: If a bacterium possesses a mutation in the gene for DNA polymerase III, resulting in an enzyme…

A: In general, DNA replication is a very accurate process. Random mistakes occasionally occur and are…

Q: Explain why the absorption of UV light by double-stranded DNA increases (the hyperchromic effect)…

A: Hyperchromicity is the effect of the increase in the absorbance of the molecule.

Q: . The DNA polymerases are positioned over the following DNA segment (which is part of a much larger…

A: Introduction  DNA replication is very crucial process for the continuation of life as every new…

Q: DNA polymerases cannot initiate DNA synthesis without a primer, a section of nucleic acid having a…

A: Primase is an RNA polymerase which produce short strand of primer required by DNA polymerase in DNA…

Q: The E. coli chromosome is 1.28 mm long. Under optimal conditions, thechromosome is replicated in 40…

A: Since we only answer up to 3 sub-parts, we’ll answer the first 3. Please resubmit the question and…