Answered: Which of these does not describe the…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Which of these does not describe the significance of glutamine in cancer cell metabolism?

Group of answer choices

It can be transaminated to alpha-ketoglutarate to drive lipid biosynthesis

Its catabolism maintains anaplerosis

It is used in the synthesis of other amino acids like alanine

It can be used to produce reactive oxygen species need to produce DNA damage

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Glutamine is a non-essential amino acid that is used by cancer cells for a variety of purposes, including -

Anaplerosis: Glutamine can be converted to alpha-ketoglutarate, which is a key intermediate in the citric acid cycle. This helps to maintain the citric acid cycle, which is essential for energy production and cell growth.
Synthesis of other amino acids: Glutamine can be used to synthesize other amino acids, such as alanine. This is important for cancer cells, as they often have a high demand for amino acids.
Production of glutathione: Glutamine can be used to produce glutathione, which is an antioxidant that helps to protect cells from damage.

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