Which of these are artificial sweeteners (Arts) and which are metabolized (Mtbs) by glycolysis? HOCH₂ (1) H HO OH H CH₂OH OH CI CH OH (2) он OH Arts; 1, 3, Mtbs; 2, 4 Arts; 2, 3, Mtbs; 1, 4 Arts; 1, 4, Mtbs; 2, 3 Arts; 3, 4, Mtbs; 1, 2 Arts; 2, 4, Mtbs; 1, 3 CH₂CI OH НО CH₂CI HỎ CHOH (3) он OH CH₂OH OH но CH OH (4) OH NH₂ OCH3

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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**Title: Identification of Artificial Sweeteners and Metabolizable Sugars**

**Question:**  
Which of these are artificial sweeteners (Arts) and which are metabolized (Mtbs) by glycolysis?

**Chemical Structures:**

1. **Structure (1):**
   - Contains a six-membered ring with multiple hydroxyl (OH) groups and a methoxy (CH₂OH) group.

2. **Structure (2):**
   - Comprised of a six-membered ring with hydroxyl (OH) groups and chlorinated alkoxy (CH₂Cl) groups.

3. **Structure (3):**
   - Similar to structure (2), it has a six-membered ring along with hydroxyl (OH) groups and a methoxy (CH₂OH) group.

4. **Structure (4):**
   - Features a more complex structure with an amide linkage, a phenyl ring, and an ester group.

**Answer Options:**

- A. Arts: 1, 3; Mtbs: 2, 4
- B. Arts: 2, 3; Mtbs: 1, 4
- C. Arts: 1, 4; Mtbs: 2, 3
- D. Arts: 3, 4; Mtbs: 1, 2
- E. Arts: 2, 4; Mtbs: 1, 3

**Explanation:**  
When identifying artificial sweeteners, look for structures common in non-caloric or low-caloric sweeteners, typically containing elements or groups such as halogens (e.g., chlorine) or large non-carbohydrate structures. Metabolizable sugars typically resemble natural sugars, often containing multiple hydroxyl groups without halogenation.

The task involves matching chemical structures with their roles as either artificial sweeteners or substances that can be metabolized through glycolysis.
Transcribed Image Text:**Title: Identification of Artificial Sweeteners and Metabolizable Sugars** **Question:** Which of these are artificial sweeteners (Arts) and which are metabolized (Mtbs) by glycolysis? **Chemical Structures:** 1. **Structure (1):** - Contains a six-membered ring with multiple hydroxyl (OH) groups and a methoxy (CH₂OH) group. 2. **Structure (2):** - Comprised of a six-membered ring with hydroxyl (OH) groups and chlorinated alkoxy (CH₂Cl) groups. 3. **Structure (3):** - Similar to structure (2), it has a six-membered ring along with hydroxyl (OH) groups and a methoxy (CH₂OH) group. 4. **Structure (4):** - Features a more complex structure with an amide linkage, a phenyl ring, and an ester group. **Answer Options:** - A. Arts: 1, 3; Mtbs: 2, 4 - B. Arts: 2, 3; Mtbs: 1, 4 - C. Arts: 1, 4; Mtbs: 2, 3 - D. Arts: 3, 4; Mtbs: 1, 2 - E. Arts: 2, 4; Mtbs: 1, 3 **Explanation:** When identifying artificial sweeteners, look for structures common in non-caloric or low-caloric sweeteners, typically containing elements or groups such as halogens (e.g., chlorine) or large non-carbohydrate structures. Metabolizable sugars typically resemble natural sugars, often containing multiple hydroxyl groups without halogenation. The task involves matching chemical structures with their roles as either artificial sweeteners or substances that can be metabolized through glycolysis.
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