Which of the following statements is not correct? +30! -F Membrane Potential (mV) H D. .B -70- A C Time (ms) Label A represents the resting membrane potential Label B represents the threshold potential Voltage-gated Na* channels are closed at the membrane potential labeled H Voltage-gated K* channels are closed at the membrane potential labeled C
Which of the following statements is not correct? +30! -F Membrane Potential (mV) H D. .B -70- A C Time (ms) Label A represents the resting membrane potential Label B represents the threshold potential Voltage-gated Na* channels are closed at the membrane potential labeled H Voltage-gated K* channels are closed at the membrane potential labeled C
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
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
Transcribed Image Text:### Understanding Membrane Potentials: Analyzing an Action Potential Graph
**Question 40**
**Which of the following statements is *not* correct?**
**Graph Description:**
The graph shows the changes in membrane potential (mV) over time (ms), highlighting different phases of an action potential in a neuron.
1. **Resting Membrane Potential (Label A)**: This is the state when a neuron is at rest, and the membrane potential is around -70 mV.
2. **Threshold Potential (Label B)**: This is the critical level to which the membrane potential must be depolarized to initiate an action potential.
3. **Depolarization (D to F)**: Upon reaching threshold (Label B), there is a rapid rise in membrane potential, moving towards a more positive value (+30 mV around Label F).
4. **Repolarization (Label G to H)**: After the peak, the membrane potential rapidly falls back towards negative values.
5. **Hyperpolarization (Label H)**: The membrane potential temporarily becomes more negative than the resting potential before stabilizing back to the resting membrane level.
**Options:**
o Label A represents the resting membrane potential
o Label B represents the threshold potential
o Voltage-gated Na⁺ channels are closed at the membrane potential labeled H
o Voltage-gated K⁺ channels are closed at the membrane potential labeled C
To correctly answer the question, identify which statement does *not* accurately describe what is occurring at the specified points or phases in the graph.
**Explanation of Correct Answer:**
- **Label A (Resting membrane potential)** is correct, as the resting membrane potential of a neuron is typically around -70 mV.
- **Label B (Threshold potential)** is correct, as the neuron must reach this level to fire an action potential.
- **Voltage-gated Na⁺ channels closed at H** is incorrect. At H (repolarization/hyperpolarization phase), voltage-gated Na⁺ channels would already be inactivated, and it’s the voltage-gated K⁺ channels that open to return the membrane potential towards the negative side.
- **Voltage-gated K⁺ channels closed at C** might create confusion, but considering that C denotes a phase post the peak of action potential, it is more correct compared to H as many K⁺ channels would have closed following the repolarization phase.
Thus, the **incorrect
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