Which of the following should inhibit the PDC by feedback inhibition? Choose all that apply.
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Q: Which Molecule Is Being Reduced In The Reation Pyruvate (C3H4O3) + NADH+H+ -> Lactate (C3H6O3)+NAD+
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Which of the following should inhibit the PDC by feedback inhibition? Choose all that apply.
NADH
NAD+
CoASH
Acetyl-CoA
Pyruvate
Glucose 6-phosphate
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- Glucagon secretion inhibits intracellular acetyl-CoA carboxylase activity through a number of different methods. Make a list of everything that comes to mind.Compare and contrast the following items related to lipid metabolism. Cite their main similarities/or differences. 1.lysophosphatidylcholine vs. phosphatidylethanolamine 2.trimyristin vs. triolein. 3. ACP vs. carnitine-acyl transferase.The peroxisomal enzyme b-ketoacyl–CoA-thiolase does notbind medium-chain acyl-CoA, in contrast to the analogousmitochondrial enzyme. Explain why this phenomenon is anadvantage to the cell.
- Which enzyme is used for both the synthesis and breakdown of acetoacetate? thiolase O HMG-CoA synthase OB-hydroxybutyrate dehydrogenase O B-Ketoacyl-CoA transferaseIn the presence of saturating amounts of oxaloacetate, the activity of citrate synthase from pig heart tissue shows a sigmoid dependence on the concentration of acetyl‑CoA. When succinyl‑CoA is added, the curve shifts to the right and the sigmoid dependence is more pronounced.Write the structure of each nucleotide-linked sugar in the pathway shown in Figure
- Which of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinasePharmaceuticals in a class called the statins inhibit theenzyme HMG-CoA reductase. What is the primary effect ofthis drug on patients?Of the allosteric enzymes listed below, which are suppressed by NADH? Select all that apply. the pyruvate dehydrogenase complex a-ketoglutarate dehydrogenase complex U isocitrate dehydrogenase pyruvate kinase Ophosphofructokinase hexokinase Oglucokinase
- Two of the steps in the oxidative decarboxylation of pyruvate (steps 4 and 5 in the figure) do not involve any of the three carbons of pyruvate, yet are essential to the operation of the pyruvate dehydrogenase (PDH) complex. CH3 Pyruvate Hydroxyethyl TPP 1 TPP TPP CHOH 1 CH3 2 Pyruvate dehydrogenase, E₁ CH3 SH Acetyl lipoyllysine 515 CoA-SH CH3- C-S-COA Acetyl-CoA Oxidized lipoyllysine. Reduced 3 lipoyllysine Dihydrolipoyl transacetylase, E₂ Lys FAD -SH SH FADH₂ Dihydrolipoyl dehydrogenase, E3 NADH + H+ NAD+. Glucagon secretion causes inhibition of intracellular acetyl-CoA car- boxylase activity by several mechanisms. Name all you can think of.Alpha-ketoglutarate dehydrogenase exhibits feedback inhibition by