The reaction catalyzed by aconitase converts citrate to isocitrate. It is strongly inhibited when itreacts with which is produced when wildlife ingests (also known as compound 1080),fluoroacetyl-CoA; fluorocitrateO fluoroacetate, fluoroacetyl-CoAOfluorocitrate, fluoroacetyl-CoAOfluorocitrate, fluoroacetate

Citrate, also known as citric acid is an organic compound. It is devoid of any colour and has a weak…

Answered: The reaction catalyzed by aconitase…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Pyruvate + NAD+ + CoA → Acetyl COA NAIDHI + H + CO₂ This is the overall reaction for the pathway of Glycolysis Oxidative decarboxylation of pyruvate Fatty acid oxidation Ellectron transport Oxidative phosphorylation TCA or citric acid cycle
A specialized lysine-linked co-enzyme often participates in the transfer of carbon fragments within an enzyme complex. Which group of three enzymes below make use of lysine-linked co-enztmes. Pyruvate dehydrogenase complex, a-Ketoglutarate dehydrogenase complex, NADH-Q oxidoreductase Pyruvate dehydrogenase complex, Succinate-Q oxidoreductase, Pyruvate carboxylase Pyruvate dehydrogenase complex, a-Ketoglutarate dehydrogenase complex, Pyruvate carboxylase Pyruvate dehydrogenase complex, Succinate-Q oxidoreductase, NADH-Qoxidoreductase Coordinate regulation occurs when different metabolic pathways are impact by a common compound. Which molecules below are compounds of coordinated regulation? Acety-CoA Molecular oxygen ATP NADH
Acetyl CoA 00-COA COA Six -carbon molecule formed from acetyl CoA + oxaloacetate Four-carbon acceptor molecule (regenerated in each cycle) O00000 Citrate One carbon lost as 5 co2 O000 Oxaloacetate NAD+ NADH NADH + CO2 NAD* Secand carbon NAD+ lost as COz NADH + COD Reduced electron carrier similar to NADH Z7 GDP, O FADH2 Energy-carrying n molecule equivalent FAD GTP to ATP
Alpha-ketoglutarate dehydrogenase exhibits feedback inhibition by
Which of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinase
Which of the following statements is true for the shown reactions? Deficiency of oxaloacetate stimulates the formation of X and y Insulin signaling stimulates the formation of X and Y Both A and B Neither A nor B
Which of the following enzymes catalyze a reaction where a ketone is converted to an acid? Alpha-ketoglutarate dehydrogenase Glyceraldehyde 3-phosphate dehydrogenase Pyruvate decarboxylase Fumarase Hexokinase
Provide the structure of the REACTANTS and PRODUCTS Step Reactants/ substrates Enzyme function Product 1 Acetyl CoA and acyl-carrier protein(ACP) and Malonyl CoA and ACP Acetyl transacylase and Malonyl transacylase transfers the acyl and the malonyl moiety to the holo-ACP molecule. Acetyl ACP and CoA and Malonyl ACP and CoA 2 Acetyl ACP and Malonyl ACP acyl-malonyl ACP condensing enzyme catalyzes the condensation reaction. Acetoacetyl ACP 3 Acetoacetyl ACP beta-ketoacyl ACP reductase enzyme catalyzes the reduction reaction and the NADPH is used as the reducing agent. D-3-hydroxybutyryl ACP. 4 D-3-hydroxybutyryl ACP. 9-hydroxyacyl ACP dehydratase enzyme catalyzes the dehydration reaction. Crotonyl ACP 5 Crotonyl ACP Enoyl ACP reductase enzyme catalyzes the reduction reaction. Butyryl ACP 6 Butyryl ACP condensation reaction C6-beta-ketoacyl ACP 7 C6-beta-ketoacyl ACP Ketoacyl-ACP reductase catalyzed the reduction reaction C6-acyl ACP 8 Palmitoyl ACP…
Which citric acid cycle enzyme utilizes a similar reaction mechanism to pyruvate dehydrogenase? O Malate dehydrogenase Isocitrate dehydrogenase O Alpha-ketoglutarate dehydrogenase Succinate dehydrogenase
The following reaction, the last reaction in beta-oxidation, is an example of a: Enzyme Enzyme-H S-CoA S-COA H2C H3C CoA s–CoA C H2 CH2 R S-COA S-COA S-COA O A. Nucleophilic acyl substitution O B. Electrophilic addition OC. Nucleophilic addition D. Aldol condensation O E. Hydrohalogenation
Under anaerobic conditions, following the radiolabel at carbon-2 of pyruvate, in which molecule does the carbon label ultimately end up so that it can be taken up by the muscle cell and used for metabolism? Lactate C-2 Glucose C-2 and C-5 Acetyl- CoA C-2 Glucose C-1 and C-6 CO2 Pyruvate C-2
[References) Which of the following statements explains why acetyl-CoA Iis considered the central molecule of metabolism? (Select all that apply.) O The addition of acetyl-CoA to compounds stabilises them. Acetyl-CoA contains a thioester bond that makes it one of the high energy compounds in metabolic pathways. O Acetyl-CoA is an inhibitor that plays a central role in regulating metabolic pathways. O Acetyl-CoA feeds directly into the citric acid cycle. U None of the above.

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