Cellular signaling follows a cascade of events and has multiple points of regulation. Which of the following could be a reason(s) why a signalling cascade is interrupted, or turned 'off', once it has been turned 'on'?
A) a protein gets tagged with an ubiqutin group and gets degraded
B) a chemical modification occurred on serine, threonine, or tyrosine side chains to turn on/off proteins
C) allosteric regulation causes an active site to be hidden
D) All of the other answers are correct
E) The ligand is prevented from reaching the binding site
It is true that cellular signalling follows a cascade of events and has multiple points of regulation. The following could be a reasons why a signalling cascade is interrupted, or turned 'off', once it has been turned 'on:
A) a protein gets tagged with an ubiquitin group and gets degraded,
B) a chemical modification occurred on serine, threonine or tyrosine side chains to turn on/off proteins and
E) the ligand is prevented from reaching the binding site.
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