When polynucleotides are synthesized with repeating triplets ofnucleotide residues, from one to three kinds of polypeptide chainswill be produced in cell-free synthesis.(a) Explain why these different results are possible.(b) Predict polypeptides produced when the following are usedwith an E. coli system: (GUA), (UUA),

Answered: When polynucleotides are synthesized…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Related questions

Question

When polynucleotides are synthesized with repeating triplets of
nucleotide residues, from one to three kinds of polypeptide chains
will be produced in cell-free synthesis.
(a) Explain why these different results are possible.
(b) Predict polypeptides produced when the following are used
with an E. coli system: (GUA), (UUA),

Expert Solution

Step 1

Polynucleotides are chain of nucleotides which are bonded together by covalent bond. The bond is formed between the phosphate of first nucleotide and the third carbon atom of the other nucleotide.

Step 2

1. Codons express themselves in the form of triplet. Each triplet refers to an amino acids. In a cell-free synthesis, as the nucleotides are repetitive in nature, the maximum three combination which can formed (if all the three nitrogen bases are different) will give rise to three different amino acids.

Thus, depending upon what the triplet is, one to three amino acids can be produced.