when calculating the Resting membrance potential using the goldman equation it is usally out, out , in / in, in, out. the cl- is switched so does that mean that when writing the in and out cellular concentartion should we still add negative sign in front of the value or since it is flipped we shouldnt?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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when calculating the Resting membrance potential using the goldman equation it is usally

out, out , in / in, in, out. the cl- is switched so does that mean that when writing the in and out cellular concentartion should we still add negative sign in front of the value or since it is flipped we shouldnt?.

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