What would most likely occur to nuclear-cytoplasmic shuttling if the intrinsic GTPase activity of RAN was slowed down by 50%?   Group of answer choices RAN would not bind exportin and proteins would accumulate in the nucleus All of the answers are likely None of the answers are likely Importin beta would not release from RAN in the cytoplasm and nuclear import would slow down RAN would not bind to importin beta and protein cargo in the nucleus would not release

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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What would most likely occur to nuclear-cytoplasmic shuttling if the intrinsic GTPase activity of RAN was slowed down by 50%?

 
Group of answer choices
  • RAN would not bind exportin and proteins would accumulate in the nucleus
  • All of the answers are likely
  • None of the answers are likely
  • Importin beta would not release from RAN in the cytoplasm and nuclear import would slow down
  • RAN would not bind to importin beta and protein cargo in the nucleus would not release
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