In this figure, the black circles and squares indicate a genetic disease. A. Based on the pedigree in the figure, does this gene appear to be inherited in a dominant or recessive manner? Explain your prediction. B. Use the letter a to indicate a disease allele and the letter A to indicate a normal allele. Predict the genotypes of the original parents. C. What percentage of the offspring of the original parents would you expect to have the disease? D. Predict the genotype of the partner of the diseased daughter in generation II. Justify your prediction.
In this figure, the black circles and squares indicate a genetic disease. A. Based on the pedigree in the figure, does this gene appear to be inherited in a dominant or recessive manner? Explain your prediction. B. Use the letter a to indicate a disease allele and the letter A to indicate a normal allele. Predict the genotypes of the original parents. C. What percentage of the offspring of the original parents would you expect to have the disease? D. Predict the genotype of the partner of the diseased daughter in generation II. Justify your prediction.
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter4: Pedigree Analysis In Human Genetics
Section: Chapter Questions
Problem 3QP: Pedigree Analysis Is a Basic Method in Human Genetics Using the pedigree provided, answer the...
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When even one member of the family has a genetic condition, analyzing the pedigree can provide information about the pattern of inheritance of the ailment and the significant threat to other family members. Gene penetrance and gene expressivity can also be estimated via pedigree analysis.
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What percent of the offspring of these parents would you expect to have the disease?
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