A man and both his parents are affected with a disease. His older brother is unaffected. This man marries a woman who is unaffected with this disease. Her father and her younger brother are affected with the same disease, but her mother and youngest brother are unaffected. Assume that this disease is caused by a single gene with two alleles with complete dominance. a. Draw the pedigree of the family above using the correct symbols and numbering.  b. What is the chance that the couple will produce an unaffected child? Please show your calculations.

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A:

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Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.