use one-letter code for amino acid if needed what is the overall amino acid sequence? A NONAPEPTIDE that attacks and kills cancer cells has just been recently isolated from a rare fungus. Aminoacid analysis of the peptide reveals the following information below: (NOTE: when the sequence is not known,a comma separates the amino acids)HydrazineAcid Hydrolysis (6 N HCI) at 110°CNonapeptide(2) Arg, Gln, (2) Tyr, Gly, Ser, Thr, and Met2,4-dinitrofluorobenzeneDNP-ThrGin andmodified freeamino acidsPeptide 1(Arg, Thr, Ser)Cleavage with Trypsin, then chromatographyPeptide 2(Gly, Tyr, Arg)MetTripeptideCyanogen bromideDipeptidePeptide 3(Arg, Ser, Tyr, Thr)Cleavage with Chymotrypsin, then chromatographyAmino acidPeptide 4(Gly, Arg, Tyr)

Sequence of a peptide can be determined by digesting the peptide with different agents that cleave…

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what is the overall amino acid sequence?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 14QP: If phenylalanine was not an essential amino acid, would diet therapy (the elimination of...

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Question

use one-letter code for amino acid if needed

what is the overall amino acid sequence?

A NONAPEPTIDE that attacks and kills cancer cells has just been recently isolated from a rare fungus. Amino
acid analysis of the peptide reveals the following information below: (NOTE: when the sequence is not known,
a comma separates the amino acids)
Hydrazine
Acid Hydrolysis (6 N HCI) at 110°C
Nonapeptide
(2) Arg, Gln, (2) Tyr, Gly, Ser, Thr, and Met
2,4-dinitrofluorobenzene
DNP-Thr
Gin and
modified free
amino acids
Peptide 1
(Arg, Thr, Ser)
Cleavage with Trypsin, then chromatography
Peptide 2
(Gly, Tyr, Arg)
Met
Tripeptide
Cyanogen bromide
Dipeptide
Peptide 3
(Arg, Ser, Tyr, Thr)
Cleavage with Chymotrypsin, then chromatography
Amino acid
Peptide 4
(Gly, Arg, Tyr)

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