What are the relative percentage (%) of species (B) and (C) at pH 7.2? (Note: treat pka's as written, i.e., no environmental/local A COOH H₂N-C-H CH₂ SH Cysteine pka₁ = 2 B COO™ H₂N-C-H CH₂ I SH Cysteine interaction effects) C COO- H₂N-C-H CH₂ S- Cysteine pkaR = 8.2 pka₂ = 10.3 D COO- H₂N-C-H CH₂ I S- Cysteine

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
Question
What are the relative percentage (%) of
species (B) and (C) at pH 7.2?
(Note: treat pka's as written, i.e., no
environmental/local
interaction effects)
A
COOH
I
H₂N-C-H
CH₂
SH
Cysteine
pka₁ = 2
B
COO-
I
H₂N-C-H
CH₂
SH
Cysteine
C
COO
I
H₂N-C-H
pka = 8.2
CH₂
S-
Cysteine
pka₂ = 10.3
D
COO™
H₂N-C-H
CH₂
S-
Cysteine
Transcribed Image Text:What are the relative percentage (%) of species (B) and (C) at pH 7.2? (Note: treat pka's as written, i.e., no environmental/local interaction effects) A COOH I H₂N-C-H CH₂ SH Cysteine pka₁ = 2 B COO- I H₂N-C-H CH₂ SH Cysteine C COO I H₂N-C-H pka = 8.2 CH₂ S- Cysteine pka₂ = 10.3 D COO™ H₂N-C-H CH₂ S- Cysteine
Expert Solution
Step 1

Amino acids contain an alpha-amino group, an alpha-carboxylic group, and a side chain. The side chain can be ionizable or non-ionizable. The side-chain of the cysteine amino acid is ionizable and it can act as a weak acid. It means the side chain of cysteine amino acid can donate a proton. 

steps

Step by step

Solved in 3 steps with 1 images

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON