What are the amino acids of the catalytic triad of chymotrypsin? State the mode catalysis shown by each of the amino acids that you have named. Predict what will happen if aspartic acid of the triad is replaced by asparagine.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter25: Nitrogen Acquisition And Amino Acid Metabolism
Section: Chapter Questions
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What are the amino acids of the catalytic triad of chymotrypsin? State the mode of
catalysis shown by each of the amino acids that you have named.
(a)
(b)
Predict what will happen if aspartic acid of the triad is replaced by asparagine.
(c)
Briefly explain the role of the oxyanion hole for the catalysis of chymotrypsin.
Transcribed Image Text:What are the amino acids of the catalytic triad of chymotrypsin? State the mode of catalysis shown by each of the amino acids that you have named. (a) (b) Predict what will happen if aspartic acid of the triad is replaced by asparagine. (c) Briefly explain the role of the oxyanion hole for the catalysis of chymotrypsin.
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