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V. Dr. Smith is incensed by the review and believes it came from a biased competitor. He clarifies with his lab that the experiment in question had been performed four times and worked twice, so they can state that they performed four repeats. He suggests that they find another statistical test that supports the "right" answer, and that extra data points be added as needed to achieve statistical significance. He asks his postdocs to find another cell line that gives the same results, another inhibitor, and another assay that can support the claims, with minimum sample sizes to complete their work within the 3-month resubmission deadline. Although a postdoc has lost some of the primary data, they agree to send just enough to satisfy the journal. Their division director is sympathetic to these efforts, and they think they understand him to say: "Because research is often handicapped by imperfect instruments and biological variability, judicious selection of methods and data is sometimes necessary to support visionary ideas and success in our tough field." 1. Which of Dr. Garcia's points are the most important problems, and which are less important? 2. How important is it to preserve original data and why? When should they be shared? 3. Are lab environment and hierarchy important for research reproducibility? How did these differ between the Smith and Garcia labs?

V. Dr. Smith is incensed by the review and believes it came from a biased competitor. He clarifies with his lab that the experiment in question had been performed four times and worked twice, so they can state that they performed four repeats. He suggests that they find another statistical test that supports the "right" answer, and that extra data points be added as needed to achieve statistical significance. He asks his postdocs to find another cell line that gives the same results, another inhibitor, and another assay that can support the claims, with minimum sample sizes to complete their work within the 3-month resubmission deadline. Although a postdoc has lost some of the primary data, they agree to send just enough to satisfy the journal. Their division director is sympathetic to these efforts, and they think they understand him to say: "Because research is often handicapped by imperfect instruments and biological variability, judicious selection of methods and data is sometimes necessary to support visionary ideas and success in our tough field." 1. Which of Dr. Garcia's points are the most important problems, and which are less important? 2. How important is it to preserve original data and why? When should they be shared? 3. Are lab environment and hierarchy important for research reproducibility? How did these differ between the Smith and Garcia labs?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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V. Dr. Smith is incensed by the review and believes it came from a biased competitor. He clarifies with his lab that the experiment in question had been performed four times and worked twice, so they can state that they performed four repeats. He suggests that they find another statistical test that supports the "right" answer, and that extra data points be added as needed to achieve statistical significance. He asks his postdocs to find another cell line that gives the same results, another inhibitor, and another assay that can support the claims, with minimum sample sizes to complete their work within the 3-month resubmission deadline. Although a postdoc has lost some of the primary data, they agree to send just enough to satisfy the journal. Their division director is sympathetic to these efforts, and they think they understand him to say: "Because research is often handicapped by imperfect instruments and biological variability, judicious selection of methods and data is sometimes necessary to support visionary ideas and success in our tough field." 1. Which of Dr. Garcia's points are the most important problems, and which are less important? 2. How important is it to preserve original data and why? When should they be shared? 3. Are lab environment and hierarchy important for research reproducibility? How did these differ between the Smith and Garcia labs?
Transcribed Image Text:V. Dr. Smith is incensed by the review and believes it came from a biased competitor. He clarifies with his lab that the experiment in question had been performed four times and worked twice, so they can state that they performed four repeats. He suggests that they find another statistical test that supports the "right" answer, and that extra data points be added as needed to achieve statistical significance. He asks his postdocs to find another cell line that gives the same results, another inhibitor, and another assay that can support the claims, with minimum sample sizes to complete their work within the 3-month resubmission deadline. Although a postdoc has lost some of the primary data, they agree to send just enough to satisfy the journal. Their division director is sympathetic to these efforts, and they think they understand him to say: "Because research is often handicapped by imperfect instruments and biological variability, judicious selection of methods and data is sometimes necessary to support visionary ideas and success in our tough field." 1. Which of Dr. Garcia's points are the most important problems, and which are less important? 2. How important is it to preserve original data and why? When should they be shared? 3. Are lab environment and hierarchy important for research reproducibility? How did these differ between the Smith and Garcia labs?
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