Homework Help is Here – Start Your Trial Now!
Science
Biology
V. Dr. Smith is incensed by the review and believes it came from a biased competitor. He clarifies with his lab that the experiment in question had been performed four times and worked twice, so they can state that they performed four repeats. He suggests that they find another statistical test that supports the "right" answer, and that extra data points be added as needed to achieve statistical significance. He asks his postdocs to find another cell line that gives the same results, another inhibitor, and another assay that can support the claims, with minimum sample sizes to complete their work within the 3-month resubmission deadline. Although a postdoc has lost some of the primary data, they agree to send just enough to satisfy the journal. Their division director is sympathetic to these efforts, and they think they understand him to say: "Because research is often handicapped by imperfect instruments and biological variability, judicious selection of methods and data is sometimes necessary to support visionary ideas and success in our tough field." 1. Which of Dr. Garcia's points are the most important problems, and which are less important? 2. How important is it to preserve original data and why? When should they be shared? 3. Are lab environment and hierarchy important for research reproducibility? How did these differ between the Smith and Garcia labs?

V. Dr. Smith is incensed by the review and believes it came from a biased competitor. He clarifies with his lab that the experiment in question had been performed four times and worked twice, so they can state that they performed four repeats. He suggests that they find another statistical test that supports the "right" answer, and that extra data points be added as needed to achieve statistical significance. He asks his postdocs to find another cell line that gives the same results, another inhibitor, and another assay that can support the claims, with minimum sample sizes to complete their work within the 3-month resubmission deadline. Although a postdoc has lost some of the primary data, they agree to send just enough to satisfy the journal. Their division director is sympathetic to these efforts, and they think they understand him to say: "Because research is often handicapped by imperfect instruments and biological variability, judicious selection of methods and data is sometimes necessary to support visionary ideas and success in our tough field." 1. Which of Dr. Garcia's points are the most important problems, and which are less important? 2. How important is it to preserve original data and why? When should they be shared? 3. Are lab environment and hierarchy important for research reproducibility? How did these differ between the Smith and Garcia labs?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question
100%
V. Dr. Smith is incensed by the review and believes it came from a biased competitor. He clarifies with his lab that the experiment in question had been performed four times and worked twice, so they can state that they performed four repeats. He suggests that they find another statistical test that supports the "right" answer, and that extra data points be added as needed to achieve statistical significance. He asks his postdocs to find another cell line that gives the same results, another inhibitor, and another assay that can support the claims, with minimum sample sizes to complete their work within the 3-month resubmission deadline. Although a postdoc has lost some of the primary data, they agree to send just enough to satisfy the journal. Their division director is sympathetic to these efforts, and they think they understand him to say: "Because research is often handicapped by imperfect instruments and biological variability, judicious selection of methods and data is sometimes necessary to support visionary ideas and success in our tough field." 1. Which of Dr. Garcia's points are the most important problems, and which are less important? 2. How important is it to preserve original data and why? When should they be shared? 3. Are lab environment and hierarchy important for research reproducibility? How did these differ between the Smith and Garcia labs?
Transcribed Image Text:V. Dr. Smith is incensed by the review and believes it came from a biased competitor. He clarifies with his lab that the experiment in question had been performed four times and worked twice, so they can state that they performed four repeats. He suggests that they find another statistical test that supports the "right" answer, and that extra data points be added as needed to achieve statistical significance. He asks his postdocs to find another cell line that gives the same results, another inhibitor, and another assay that can support the claims, with minimum sample sizes to complete their work within the 3-month resubmission deadline. Although a postdoc has lost some of the primary data, they agree to send just enough to satisfy the journal. Their division director is sympathetic to these efforts, and they think they understand him to say: "Because research is often handicapped by imperfect instruments and biological variability, judicious selection of methods and data is sometimes necessary to support visionary ideas and success in our tough field." 1. Which of Dr. Garcia's points are the most important problems, and which are less important? 2. How important is it to preserve original data and why? When should they be shared? 3. Are lab environment and hierarchy important for research reproducibility? How did these differ between the Smith and Garcia labs?
Expert Solution
steps

Step by step

Solved in 3 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Analytical Methods
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS