Question in photo 5. Consider the use of GWAS to identify mutations that contribute to an increased risk ofpancreatic cancer or to pancreatic cancer phenotypes. For a GWAS you have access to twopopulations: those with cancer, those without. What results would you expect to find if theDNA samples were taken from non-cancer tissues from both populations? How would thiscompare to results if you used DNA from cancer samples (pancreatic cancer biopsy) vs.healthy pancreatic tissue? State any assumptions you are making.

Cancer is a highly fatal disease that may occur due to the exposure towards high ultra violet rays. It can cause severe damage to the cells owing to the death of the person.Cancer and non cancer DNA. A biopsy can be used to differentiate a cancerous cells from the non cancerous cells. The DNA of the cancerous cells is seen to be highly mutated. This muttation may cause the formation of altered proteins during the synthesis of proteins. The mutation in the cells are due to the result of the smoking or any kind of genetic inheritance. But the DNA of the non cancerous cells are normal without muttation. Cancer and non cancer tissue Now by examining the tissue we can easily find that the cells are cancerous or non cancerous. The cells which are cancerous cimtains a tumor which has a uncontrolled cell growth and covers the whole tissue damaging it. This type of abnormal growth of cell in a tissue or organ is called hyperplasia. However the non cancerous cells are devoid of the tumor cells and is normal. Conclusion Thus from the above explanation the concept of the distinguishing features of the cancerous and non cancerous cells can be understood easily.