Use this information and Bayes theorem to calculate the predictive value negative of the allopurinol screening test.
Use this information and Bayes theorem to calculate the predictive value negative of the allopurinol screening test.
Glencoe Algebra 1, Student Edition, 9780079039897, 0079039898, 2018
18th Edition
ISBN:9780079039897
Author:Carter
Publisher:Carter
Chapter4: Equations Of Linear Functions
Section: Chapter Questions
Problem 8SGR
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Topic Video
Question
A researcher calculated the negative predictive value of a
test for carriers of X-linked ornithine transcarbamylase deficiency
(OTCD - a disorder of the urea cycle). A test known as the “allopurinol
test" is often used as a screening device of potential carriers whose
relatives are OTCD patients. Sensitivity and specificity of the
allopurinol test is estimated as 0.927 and 0.997 respectively Also the
prevalence is estimated in the population of individuals with OTCD as
(1/32000). Use this information and Bayes theorem to calculate the
predictive value negative of the allopurinol screening test.
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