A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving eight participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later Is there a statistically significant difference in blood pressures over time? Run the test at a 5% level of significance. Give each of the following to receive full credit: 1) the appropriate null and alternative hypotheses; 2) the appropriate test; 3) the decision rule; 4) the calculation of the test statistic; and 5) your conclusion including a comparison to alpha or the critical value. Baseline 4 weeks 135 136 145 142 133 135 160 158 152 155 143 140 129 128 146 129
A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving eight participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later Is there a statistically significant difference in blood pressures over time? Run the test at a 5% level of significance. Give each of the following to receive full credit: 1) the appropriate null and alternative hypotheses; 2) the appropriate test; 3) the decision rule; 4) the calculation of the test statistic; and 5) your conclusion including a comparison to alpha or the critical value.
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Baseline
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4 weeks
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135
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136
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145
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142
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133
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135
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160
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158
|
|
152
|
155
|
|
143
|
140
|
|
129
|
128
|
|
146
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129
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