Two components of a 12-mg sample are adequately separated by chromatography through a column 1.5 cm in diameter and 25 cm long at a flow rate of 0.8 mL/min. What size column and what flow rate should be used to obtain similar separation with a 250-mg sample?

Fundamentals Of Analytical Chemistry
9th Edition
ISBN:9781285640686
Author:Skoog
Publisher:Skoog
Chapter32: Gas Chromatography
Section: Chapter Questions
Problem 32.12QAP
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Two components of a 12-mg sample are adequately separated by chromatography through a column 1.5 cm in diameter and 25 cm long at a flow rate of 0.8 mL/min. What size column and what flow rate should be used to obtain similar separation with a 250-mg sample?

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