Trihexphenidyl is a muscarinic antagonist. Based on SAR to preserve the activity which one is not correct. OH 00 a. OH group can be changed with hydroxymethyl. b. You can change the cyclohexyl with a phenyl ring c. C1 carbon is interchangeable with O d. You can change N containing piperidine group to cyclopentyl e. OH group increases antagonistic activity

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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1-
Trihexphenidyl is a muscarinic
antagonist. Based on SAR to
preserve the activity which one
is not correct.
OH
Of C
a. OH group can be changed with
hydroxymethyl.
b. You can change the cyclohexyl with a
phenyl ring
c. C1 carbon is interchangeable with O
d. You can change N containing piperidine
group to cyclopentyl
e. OH group increases antagonistic activity
Transcribed Image Text:1- Trihexphenidyl is a muscarinic antagonist. Based on SAR to preserve the activity which one is not correct. OH Of C a. OH group can be changed with hydroxymethyl. b. You can change the cyclohexyl with a phenyl ring c. C1 carbon is interchangeable with O d. You can change N containing piperidine group to cyclopentyl e. OH group increases antagonistic activity
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